Patents by Inventor Derek C. Burke

Derek C. Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody to interferon-.alpha.
    Patent number: 4423147
    Abstract: A monoclonal antibody is described characterized by its specificity to interferon-.alpha. (leukocyke interferon). Preferably the antibody has specificity to human interferon-.alpha.. The monoclonal antibody is secreted by a hybrid cell formed by the fusion of lymphocyte cells derived from an animal immunized with interferon-.alpha., with mycloma cells. The antibody has applications in the purification of interferon. It may be covalently attached to a solid support and used as an immunoadsorbent. Purifications of up to 5000 fold may be obtained in a single pass through an immunoadsorption column of this type. An immunoradiometric assay for interferon-.alpha. is also described.
    Type: Grant
    Filed: December 10, 1981
    Date of Patent: December 27, 1983
    Inventors: David S. Secher, Derek C. Burke