Abstract: The application provides compositions including engineered reverse transcriptases with at least one altered reverse-transcriptase related activity. The engineered reverse transcriptases or reverse transcription enzymes unexpectedly exhibit one or more altered reverse transcriptase related activities such as but not limited to altered template switching efficiency, altered transcription efficiency or both.

Abstract: The present invention discloses a wirelessly controlled vehicle that is configured to travel in air, on liquid and under liquid with an ability to communicate with a remote operator through wireless communication.

Abstract: Saw blades and methods of machining saw blade tooth profiles of saw blades. The saw blades include a blade body and a plurality of teeth defined by the blade body. Each tooth includes a tooth back, a tooth tip, a tooth face, and a tooth gullet. In at least one tooth, a relief region extends toward the tooth back and separates the tooth face from the tooth gullet. The methods include supporting the saw blade with a blade support structure and advancing the saw blade with a blade advance structure. The methods also include dry-machining a finished tooth profile in a working portion of the saw blade in a single pass. The dry-machining includes dry-machining with an end mill by operatively translating the end mill relative to the saw blade and within a plane that is at least substantially perpendicular to an end mill rotational axis of the end mill.

Abstract: In one embodiment, a medical circuit component for use with humidified gases is described. The medical circuit conduit includes: a body comprising a wall having an inner surface that defines a space within which humidified gases may flow and/or be contained; and moisture transport means and/or element(s) at least partially coupled to and/or at least partially integrated into at least a part of the wall, the moisture transport means and/or element(s) being configured to receive moisture from vapors and/or liquid inside the space and transport at least some of said moisture away from where it was received.

Abstract: Saw blades and methods of machining saw blade tooth profiles of saw blades. The saw blades include a blade body and a plurality of teeth defined by the blade body. Each tooth includes a tooth back, a tooth tip, a tooth face, and a tooth gullet. In at least one tooth, a relief region extends toward the tooth back and separates the tooth face from the tooth gullet. The methods include supporting the saw blade with a blade support structure and advancing the saw blade with a blade advance structure. The methods also include dry-machining a finished tooth profile in a working portion of the saw blade in a single pass. The dry-machining includes dry-machining with an end mill by operatively translating the end mill relative to the saw blade and within a plane that is at least substantially perpendicular to an end mill rotational axis of the end mill.

Abstract: A circular saw blade indexing assembly includes a base and a circular saw blade mounting assembly connected to the base and having a saw hub configured to support a circular saw blade. The circular saw blade indexing assembly includes an indexing mechanism connected to the base and having a feed finger disposed at a radial distance from the saw hub, the feed finger configured to rotate the circular saw blade about the saw hub between a first arc position and a second arc position. The circular saw blade indexing assembly includes a radius adjustment mechanism configured to adjust a relative longitudinal position between the saw hub of the circular saw blade mounting assembly and the feed finger of the indexing mechanism.

Abstract: Systems and methods for milling saw blade tooth profiles and saw blades with milled tooth profiles are disclosed herein. The systems include blade milling systems that include a milling head, a blade support structure, a blade advance structure, and a control system. The methods include supporting a saw blade, advancing the saw blade, and machining a finished tooth profile in a working portion of the saw blade with an end mill. In some embodiments, the machining may include operatively translating the end mill relative to the saw blade with a milling head and within a plane that is at least substantially perpendicular to an end mill rotational axis. In some embodiments, the machining may include dry-machining the finished tooth profile in the working portion of the saw blade in a single pass. The saw blades include a plurality of teeth and may include at least one relief region.

Abstract: Systems and methods for milling saw blade tooth profiles and saw blades with milled tooth profiles are disclosed herein. The systems include blade milling systems that include a milling head, a blade support structure, a blade advance structure, and a control system. The methods include supporting a saw blade, advancing the saw blade, and machining a finished tooth profile in a working portion of the saw blade with an end mill. In some embodiments, the machining may include operatively translating the end mill relative to the saw blade with a milling head and within a plane that is at least substantially perpendicular to an end mill rotational axis. In some embodiments, the machining may include dry-machining the finished tooth profile in the working portion of the saw blade in a single pass. The saw blades include a plurality of teeth and may include at least one relief region.

Abstract: An aircraft assembly including a first part having a pin and a second part having a hook that is movable in an engagement plane to engage the pin to hold the first part in a condition relative to the second part. The pin has a prominent central portion and one or more axially spaced outer portions, the prominent portion is prominent with respect to the outer portions in the engagement plane to cause contact to be made between the hook and the pin within the central portion of the pin, rather than the outer portions of the pin.

Abstract: A circular saw blade indexing assembly includes a base and a circular saw blade mounting assembly connected to the base and having a saw hub configured to support a circular saw blade. The circular saw blade indexing assembly includes an indexing mechanism connected to the base and having a feed finger disposed at a radial distance from the saw hub, the feed finger configured to rotate the circular saw blade about the saw hub between a first arc position and a second arc position. The circular saw blade indexing assembly includes a radius adjustment mechanism configured to adjust a relative longitudinal position between the saw hub of the circular saw blade mounting assembly and the feed finger of the indexing mechanism.

Abstract: An aircraft assembly including a first part having a pin and a second part having a hook that is movable in an engagement plane to engage the pin to hold the first part in a condition relative to the second part. The pin has a prominent central portion and one or more axially spaced outer portions, the prominent portion is prominent with respect to the outer portions in the engagement plane to cause contact to be made between the hook and the pin within the central portion of the pin, rather than the outer portions of the pin.

Abstract: A submarine homing system includes an acoustic emitter configured to emit an acoustic signal comprising at least two narrow-band tones, each narrow-band tone having a respective predetermined center frequency. An acoustic receiver is configured to receive the acoustic signal from the acoustic emitter, and produce one or more receiver signals. A processor is operatively connected to the acoustic receiver. The processor is configured to process the receiver signals to calculate a direction between the acoustic receiver and the acoustic emitter.

Abstract: A submarine homing system includes an acoustic emitter configured to emit an acoustic signal comprising at least two narrow-band tones, each narrow-band tone having a respective predetermined center frequency. An acoustic receiver is configured to receive the acoustic signal from the acoustic emitter, and produce one or more receiver signals. A processor is operatively connected to the acoustic receiver. The processor is configured to process the receiver signals to calculate a direction between the acoustic receiver and the acoustic emitter.

Abstract: Embodiments of a temperature control case and related methods and systems are disclosed. Some embodiments may be particularly useful for portable storage of temperature-sensitive pharmaceutical substances and the like. Embodiments are also disclosed which are configured specifically for cooling intravenous fluids to be used for therapeutic hypothermia. Some embodiments may include multiple storage compartments each being configured to store substances at a different temperature so that intravenous fluids can be stored in one compartment and other substances in another compartment. Some embodiments include both internal and external temperature sensors to allow the device to predict internal temperature changes and adjust heating/cooling elements accordingly before the internal temperature is unduly impacted by the ambient temperature, thereby increasing the efficiency and efficacy of the temperature control system.

Abstract: A putting training system is described which includes a modified putter head and may include a modified golf ball. The putter head includes sensor prongs which project from the putter head face.

Abstract: A website development system and an optimizing sub-system is capable of instructing a user on measures to customize a website in order to increase visibility of the website to website search engines. The optimizing sub-system analyzes content provided by the user, or otherwise generated for the user, and notifies the user if the system is optimized or needs additional optimization. The website development system may be capable of generating content, such as text and images, which may be optimized for search engine visibility, such as appropriate length of text paragraphs, keyword usage, keyword density, and other optimization protocols. The website development system may provide an interactive system for a user to develop a website that encourages the user to complete the steps in the development process. The website development system is able to organize content in a list of component parts. Each component part is a building block.

Abstract: The invention provides peptide antagonists, such as synthetic collagen peptides. The invention provides antibody antagonists, or functional fragments thereof, that preferentially bind to denatured extracellular matrix components. It additionally provides methods for using the antagonists for inhibiting angiogenesis, tumor metastasis, and other tumor developmental processes, including cell migration, cell adhesion, cell proliferation, and tumor growth and for treating angiogenesis-dependent conditions or collagen-dependent conditions. The application also provides for use of the antagonists as a vaccine for inducing an immune response, immune focusing and induction of antibody responses.

Abstract: A website development system and an optimizing sub-system is capable of instructing a user on measures to customize a website in order to increase visibility of the website to website search engines. The optimizing sub-system analyzes content provided by the user, or otherwise generated for the user, and notifies the user if the system is optimized or needs additional optimization. The website development system may be capable of generating content, such as text and images, which may be optimized for search engine visibility, such as appropriate length of text paragraphs, keyword usage, keyword density, and other optimization protocols. The website development system may provide an interactive system for a user to develop a website that encourages the user to complete the steps in the development process.

Abstract: An assistive device for persons with an injured or disabled leg includes a main body comprising a crutch to which is pivotally attached a supporting structure. To assist the person in walking, the device can be used as crutch in the known manner, and the supporting structure is maintained in the same plane as the crutch. When the person wishes to be seated, one end of the device is placed on the seat adjacent the person and the supporting structure of the device is pivoted out of the plane of the crutch to provide a support for the opposite end.