Abstract: Systems and methods for multi-modal imaging using an endoscope having an instrument channel, where the imaging is achieved without using the channel, are disclosed. The systems can include a multi-modal imaging paddle housing couple to a distal end of the endoscope. The housing can receive at least two imaging probes. The imaging probes can be an angle-resolved low-coherence interferometry probe (a/LCI) and an optical coherence tomography (OCT) probe. The housing can be scaled and positioned to be visible via the endoscope camera. The system and method can include locating the housing in a region of interest using the endoscope camera, acquiring OCT measurements to identify targets, and then acquiring a/LCI measurements at the identified targets.

Abstract: The present disclosure provides a gas sensor comprising a gas sensing layer fabricated based on a solution-processed, template-free synthesis method that achieves controllable ZnO nanostructured morphologies. The method is based on promotion and suppression of growth at specific crystallographic dimensions by tuning the polarity of the solvent. The gas sensing layer with the ZnO nanostructures exhibits high response, excellent selectivity and rapid recovery time.

Abstract: A power amplifier includes an active device and an output matching circuit operably connected with the active device. The output matching circuit includes a bandpass impedance transformer, in particular, a multimode bandpass impedance transformer. The multimode bandpass impedance transformer may include a multimode resonator and coupling feed lines.

Abstract: A Doherty power amplifier circuit having a main power amplification device, an auxiliary power amplification device arranged in parallel with the main power amplification device, and a load modulation circuit comprising a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to transfer harmonic components generated at the main power amplification device to the auxiliary power amplification device and harmonic components generated at the auxiliary power amplification device to the main power amplification device, when both the main and auxiliary power amplification devices are operating, for modulating the respective outputs of the main power amplification device and the auxiliary power amplification device.

Abstract: Systems and methods for multi-modal imaging using an endoscope having an instrument channel, where the imaging is achieved without using the channel, are disclosed. The systems can include a multi-modal imaging paddle housing couple to a distal end of the endoscope. The housing can receive at least two imaging probes. The imaging probes can be an angle-resolved low-coherence interferometry probe (a/LCI) and an optical coherence tomography (OCT) probe. The housing can be scaled and positioned to be visible via the endoscope camera. The system and method can include locating the housing in a region of interest using the endoscope camera, acquiring OCT measurements to identify targets, and then acquiring a/LCI measurements at the identified targets.

Abstract: A power amplifier includes an active device and an output matching circuit operably connected with the active device. The output matching circuit includes a bandpass impedance transformer, in particular, a multimode bandpass impedance transformer. The multimode bandpass impedance transformer may include a multimode resonator and coupling feed lines.

Abstract: The present disclosure provides a gas sensor comprising a gas sensing layer fabricated based on a solution-processed, template-free synthesis method that achieves controllable ZnO nanostructured morphologies. The method is based on promotion and suppression of growth at specific crystallographic dimensions by tuning the polarity of the solvent. The gas sensing layer with the ZnO nanostructures exhibits high response, excellent selectivity and rapid recovery time.

Abstract: A Doherty power amplifier having a main power amplification device and an auxiliary power amplification device arranged in parallel with the main power amplification device includes a load modulation circuit having a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to provide a phase shift to simultaneously modulate transfer of second harmonic components generated at the main power amplification device to the auxiliary power amplification device and transfer of second harmonic components generated at the auxiliary power amplification device to the main power amplification device, when the main power amplification device and the auxiliary power amplification device are operated at saturation.

Abstract: A Doherty power amplifier circuit having a main power amplification device, an auxiliary power amplification device arranged in parallel with the main power amplification device, and a load modulation circuit comprising a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to transfer harmonic components generated at the main power amplification device to the auxiliary power amplification device and harmonic components generated at the auxiliary power amplification device to the main power amplification device, when both o the main and auxiliary power amplification devices are operating, for modulating the respective outputs of the main power amplification device and the auxiliary power amplification device.

Abstract: A Doherty power amplifier circuit having a main power amplification device, an auxiliary power amplification device arranged in parallel with the main power amplification device, and a load modulation circuit comprising a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to transfer harmonic components generated at the main power amplification device to the auxiliary power amplification device and harmonic components generated at the auxiliary power amplification device to the main power amplification device, when both the main and auxiliary power amplification devices are operating, for modulating the respective outputs of the main power amplification device and the auxiliary power amplification device.

Abstract: A Doherty power amplifier having a main power amplification device and an auxiliary power amplification device arranged in parallel with the main power amplification device includes a load modulation circuit having a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to provide a phase shift to simultaneously modulate transfer of second harmonic components generated at the main power amplification device to the auxiliary power amplification device and transfer of second harmonic components generated at the auxiliary power amplification device to the main power amplification device, when the main power amplification device and the auxiliary power amplification device are operated at saturation.

Abstract: A Doherty power amplifier circuit having a main power amplification device, an auxiliary power amplification device arranged in parallel with the main power amplification device, and a load modulation circuit comprising a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to transfer harmonic components generated at the main power amplification device to the auxiliary power amplification device and harmonic components generated at the auxiliary power amplification device to the main power amplification device, when both the main and auxiliary power amplification devices are operating, for modulating the respective outputs of the main power amplification device and the auxiliary power amplification device.

Abstract: A method for determining a concentration of an analyte in a subject includes irradiating a part of the subject with electromagnetic radiation, wherein a part of the subject comprises biological molecules arranged to absorb the electromagnetic radiation and to emit fluorescence in response. The method also includes measuring fluorescence emitted to obtain data representative of a fluorescence decay. The method further includes processing the data to determine one or more feature points associated with the fluorescence decay and to generate one or more feature vectors based on the one or more feature points, and applying the one or more feature vectors to a regression model for the analyte to determine the concentration of the analyte. Also provided is a system for determining a concentration of an analyte in a subject, as well as a measurement device for facilitating determination of a concentration of an analyte in a subject.

Abstract: A Doherty power amplifier includes a main device in a main amplifier circuit and an auxiliary device in an auxiliary amplifier circuit arranged in parallel with the main amplifier circuit. The Doherty power amplifier further includes a load modulation network including a first open-circuited transmission line connected to an output of the main device; a second open-circuited transmission line connected to an output of the auxiliary device; and an impedance transformation and phase compensation network connected with the output of the main device and the output of the auxiliary device for providing a combined output power. The first and second open-circuited transmission lines are arranged directly adjacent one another to form, during operation, a mutual coupling therebetween.

Abstract: A method for determining a concentration of an analyte in a subject includes irradiating a part of the subject with electromagnetic radiation, wherein a part of the subject comprises biological molecules arranged to absorb the electromagnetic radiation and to emit fluorescence in response. The method also includes measuring fluorescence emitted to obtain data representative of a fluorescence decay. The method further includes processing the data to determine one or more feature points associated with the fluorescence decay and to generate one or more feature vectors based on the one or more feature points, and applying the one or more feature vectors to a regression model for the analyte to determine the concentration of the analyte. Also provided is a system for determining a concentration of an analyte in a subject, as well as a measurement device for facilitating determination of a concentration of an analyte in a subject.

Abstract: Systems, methods and computer program products for facilitating the prognosis of degenerative disc disorder (DDD) are provided. In one aspect, intervertebral disc loss is predicted based on receiving image data comprising one or more images of the human spine; segmenting, using a processor, disc regions of said one or more images; generating, using the processor, individual biomarkers based on texture features of said segmented disc regions; generating, using the processor, a predicting intervertebral disc loss based in part on the prognostic marker generated from the individual biomarkers.

Abstract: Systems, methods and computer program products for facilitating the prognosis of degenerative disc disorder (DDD) are provided. In one aspect, intervertebral disc loss is predicted based on receiving image data comprising one or more images of the human spine; segmenting, using a processor, disc regions of said one or more images; generating, using the processor, individual biomarkers based on texture features of said segmented disc regions; generating, using the processor, a predicting intervertebral disc loss based in part on the prognostic marker generated from the individual biomarkers.

Abstract: According to one aspect of the invention, there is provided an oral debris removal device including: a suction unit; a tube in fluid communication with the suction unit, the tube having a tip portion adapted to allow introduction of oral debris into the tube via the tip portion; and a light source positioned to illuminate the tip portion of the tube and a region adjacent to the tip portion of the tube. The oral debris removal device may further include a debris collector chamber coupled between an end section of the suction unit and an end section of the tube. The debris collector chamber may include an internal protruding element disposed along an air flow path across a space between the end section of the suction unit and the end section of the tube, the internal protruding element adapted to prevent oral debris and liquid exiting the tube from entering the suction unit.

Abstract: According to one aspect of the invention, there is provided an oral debris removal device including: a suction unit; a tube in fluid communication with the suction unit, the tube having a tip portion adapted to allow introduction of oral debris into the tube via the tip portion; and a light source positioned to illuminate the tip portion of the tube and a region adjacent to the tip portion of the tube. The oral debris removal device may further include a debris collector chamber coupled between an end section of the suction unit and an end section of the tube. The debris collector chamber may include an internal protruding element disposed along an air flow path across a space between the end section of the suction unit and the end section of the tube, the internal protruding element adapted to prevent oral debris and liquid exiting the tube from entering the suction unit.

Abstract: In a two-way paging system including a paging terminal, a plurality of paging transmitters, a plurality of paging receivers, and a plurality of two-way paging units, the plurality of two-way paging units transmitting reverse channel messages to the paging receivers in a time division multiplexed protocol, the protocol including a frame with a plurality of reverse channel time slots, a method of assigning reverse channel time slots to the paging units is disclosed. The method comprises: (a) determining a set of transmitting paging units from the plurality of two-way paging units, the set of transmitting paging units being those of the plurality of two-way paging units that are to transmit a reverse channel message; and (b) randomly assigning each of the transmitting paging units in the set of transmitting paging units one of the reverse channel time slots in the frame.