Patents by Inventor Derek Huffman

Derek Huffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250099550
    Abstract: A method for treating Alzheimer's disease and related dementias and for slowing or delaying aging and prolonging life, comprising reducing circulating IGF-1 levels by administering to the patient an effective amount of a human growth hormone receptor antagonist, comprising human growth hormone receptor antagonist G120K, wherein a single amino acid of the human growth hormone receptor antagonist G120K has been mutated to cysteine, and wherein the single amino acid mutated to cysteine is T142; and a polydispersed 40 kDa branched polyethylene glycol molecule conjugated to the substituted cysteine in the human growth hormone receptor antagonist G120K mutant, wherein reducing circulating IGF-1 levels reduces the effects of Alzheimer's disease and related dementias and slows or delays aging and prolongs life.
    Type: Application
    Filed: September 23, 2024
    Publication date: March 27, 2025
    Inventors: Richard S. Brody, Thomas J. Zupancic, Uday Sandbhor, John J. Kopchick, Reetobrata Basu, Sofiya Milman, Derek Huffman
  • Publication number: 20210332141
    Abstract: The present disclosure provides a method of improvement, preservation, prophylaxis, or inhibition-of-deterioration of a healthspan parameter of a mammalian subject. In exemplary embodiments, the method comprises administering to the subject a composition that comprises an insulin-like growth factor-1 receptor (IGF-1 R) inhibitor, wherein the composition is administered in an amount effective to improve, provide prophylaxis for, or inhibit-the-deterioration of the healthspan parameter.
    Type: Application
    Filed: August 30, 2018
    Publication date: October 28, 2021
    Inventors: Pedro Beltran, Derek Huffman, Nir Brazilal, Pinchas Cohen