Patents by Inventor Derek J. Denhart

Derek J. Denhart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NK-1 and serotonin transporter inhibitors
    Patent number: 8383821
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: February 26, 2013
    Assignee: Bristol-Meyers Squibb Company
    Inventors: Andrew P. Degnan, Kevin W. Gillman, Derek J. Denhart, Jonathan L. Ditta, Ramkumar Rajamani, Ying Han, George O. Tora
  • Substituted heterocyclic ethers and their use in CNS disorders
    Patent number: 8026257
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: September 27, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andrew P. Degnan, George O. Tora, Derek J. Denhart, Vivekananda M. Vrudhula, John E. Macor, Joanne J. Bronson
  • NK-1 and Serotonin Transporter Inhibitors
    Publication number: 20100087434
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.
    Type: Application
    Filed: November 13, 2009
    Publication date: April 8, 2010
    Inventors: Andrew P. Degnan, Kevin W. Gillman, Derek J. Denhart, Jonathan L. Ditta, Ramkumar Rajamani, Ying Han, George O. Tora
  • Substituted Heterocyclic Ethers and Their Use in CNS Disorders
    Publication number: 20090018132
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
    Type: Application
    Filed: July 1, 2008
    Publication date: January 15, 2009
    Inventors: Andrew P. Degnan, George O. Tora, Derek J. Denhart, Vivekananda M. Vrudhula, John E. Macor, Joanne J. Bronson
  • Neurotrophic diamide and carbamate agents
    Patent number: 6228872
    Abstract: The present invention relates to the design, synthesis, and the peptidyl-prolyl isomerase (PPIase or rotamase) inhibitory activity of novel pyrrolidinemethyl diamide and carbamate compounds that are neurotrophic agents (i.e. compounds capable of stimulating growth or proliferation of nervous tissue) and that bind to immunophilins such as FKBP12 and inhibit their rotamase activity. This invention also relates to pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: May 8, 2001
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gene M. Dubowchik, Jonathan L. Ditta, David P. Provencal, Derek J. Denhart