Patents by Inventor Derek J. Pyle

Derek J. Pyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of lipoproteins
    Patent number: 6538118
    Abstract: Heterologous lipidated proteins formed recombinantly are disclosed and claimed. The expression system can be E. coli. The heterologous lipidated protein has a leader sequence which does not naturally occur with the protein portion of the lipidated protein. The lipidated protein can have the Borrelia OspA leader sequence. The protein portion can be OspC, PspA, UreA, Ure B, or a fragment thereof. Methods and compositions for forming and employing the proteins are also disclosed and claimed.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: March 25, 2003
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert C. Huebner, Lorne F. Erdile, Donald J. Warakomski, Jr., Robert S. Becker, Maryann B. Gray, Derek J. Pyle