Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: A method at a server for container location verification within a container yard, the method including requesting image data from at least one image sensor apparatus affixed to a container within the container yard; receiving the image data; and processing the image data to identify a location of a target container.

Abstract: Fire protection systems and methods having piping interconnections for connecting a fire protection device to a fluid source. The piping interconnections include a branch connector connected to a pipe header. The branch connector includes a tubular member and an internal annular seal member housed in an internal gasket chamber of the tubular member. The tubular member includes an internal stepless surface between a terminal end of the tubular member and the internal gasket chamber.

Abstract: The present invention is directed to a tread and a tire having a tread, wherein over most of a circumferential length i) a maximum axial width in a top portion of a tread groove is at least 5% smaller than an axial width of the tread groove in its bottom portion, ii) the axial width of the tread groove in the bottom portion is at least 5% smaller than the maximum axial width of the tread groove in a radial intermediate portion of the tread groove, and iii) a maximum axial width of the tread groove in the intermediate portion is within a range of 15% to 50% of the total radial height of the tread groove.

Abstract: An implantable medical device is disclosed. The implantable medical device includes a housing forming an internal compartment. The housing includes a frame disposed within the internal compartment forming a first partition and a second partition within the internal compartment. The first partition is hermetically sealed from the second partition. At least one electronic component and a power source are disposed within the first partition. The medical device includes a fluidics circuit including a manifold operably coupled to at least one fluidics component. The fluidics circuit is operably coupled to the at least one electronic component across the frame.

Abstract: A tire comprising a tire tread having a tread region comprising a first and second rib, wherein the first and second ribs are separated by a groove; at least one tie-bar element disposed within the groove, and the tie-bar block element having opposed sidewalls separated by a radially extending groove, wherein the radially extending groove tapers from a first width to a second width, wherein the second width is wider than the first width.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: The invention provides a novel synthetic route for the preparation of the Chk-1 inhibitor compound: as well as novel process intermediates per se.

Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.

Abstract: A breather used for vacuum bag compaction of a composite laminate part is semi-permanently installed on a compaction tool. The breather is a channel member having an internal passageway that routes air and volatiles from the vacuum bag to a vacuum port in the tool.

Abstract: A medical device includes a first housing section with a first cavity and including a ceramic material, a second housing section coupled to the first housing section and including a second cavity, a first circuit board section positioned within the first cavity, a second circuit board section positioned within the second cavity, and an antenna coupled to the first circuit board section.

Abstract: Fire protection systems and methods having piping interconnections for connecting a fire protection device to a fluid source. The piping interconnections include a branch connector connected to a pipe header. The branch connector includes a tubular member and an internal annular seal member housed in an internal gasket chamber of the tubular member. The tubular member includes an internal stepless surface between a terminal end of the tubular member and the internal gasket chamber.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: Forming systems and methods for forming an elongate charge of composite material are disclosed herein. The forming systems include an elongate forming tool having an elongate forming surface with a forming surface shape. The forming systems also include an elongate end effector, which is configured to tension the elongate charge of composite material across the elongate forming surface. The elongate end effector includes an elongate vacuum distribution manifold, a porous elongate vacuum region that is defined by a strip of porous material, and an elongate friction surface that is defined by a strip of friction material. The strip of friction material is proximate a trailing edge of the elongate end effector relative to the strip of porous material. The methods include tensioning an elongate charge of composite material across an elongate forming surface of an elongate forming tool utilizing an elongate end effector.

Abstract: Helmets for applying a magnetic field to the head of a subject, comprising: a housing comprising a concave surface configured to receive a portion of the head of the subject; a motor coupled to one or more of: a first permanent magnet via a first axle along a first axis of rotation, wherein the first axle drives movement of the first magnet; a second magnet via a second axle along a second axis of rotation wherein the second axle drives movement of the second magnet; and a third magnet via a third axle along the third axis of rotation wherein the third axle drives movement of the third magnet, wherein the axes are parallel; and a fit mechanism comprising a adjuster coupled to the first magnet, wherein movement of the adjustor moves the first magnet independently of the second or the third magnet.

Abstract: A proportioner having a body portion that defines a foam passage and a fluid passage. The proportioner also includes a restrictor assembly having a restrictor disk and an orifice plate having an opening for receiving the restrictor disk. The proportioner can further include a rod member connected to the restrictor disk and a clapper assembly connected to the rod member via a sliding interface. The clapper assembly can be configured to control a flow of the foam concentrate through the foam passage in proportion to a flow of the fire protection fluid through the fluid passage by moving the rod member to vary the distance between the restrictor disk and the orifice plate. The sliding interface can be disposed between a first guide and a second guide, and at least a portion of the restrictor disk is disposed in the opening.

Abstract: A method of reducing an effect of known computer based skills in a backgammon game includes the steps of arranging the playing pieces from farthest from home to closest to home in stacks of 1, 2, 3, 4 and 5 playing pieces, respectively, for each of a first player and a second player, and using at least two dice for each roll such that each of the first player and the second player is enabled to make at least two moves after each roll of the dice.