Patents by Inventor Derek John Londesbrough

Derek John Londesbrough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
    Patent number: 12377112
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat neurocognitive disorders (e.g., Alzheimer's disease, Parkinson's disease), ADHD, Epilepsy, Autism, Sleep-wake disorders, Chronic pain, Inflammatory Disorders, IBD, Stroke, ALS, and/or Multiple Sclerosis.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: August 5, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Hans Ake Eriksson, George Goldsmith, Ekaterina Malievskaia, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 12312375
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: July 9, 2024
    Date of Patent: May 27, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20250122232
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 17, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20240360162
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: July 9, 2024
    Publication date: October 31, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF A CHK1 INHIBITOR COMPOUND
    Publication number: 20240287035
    Abstract: The invention provides a novel synthetic route for the preparation of the Chk-1 inhibitor compound: as well as novel process intermediates per se.
    Type: Application
    Filed: June 1, 2022
    Publication date: August 29, 2024
    Applicants: SENTINEL ONCOLOGY LIMITED, PHARMAENGINE, INC.
    Inventors: Stuart TRAVERS, Meriel MAJOR, Derek John LONDESBROUGH, Richard CHUBB
  • METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20240252521
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: November 29, 2023
    Publication date: August 1, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Åke ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anaïs SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20240199660
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: February 5, 2024
    Publication date: June 20, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11939346
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: April 17, 2023
    Date of Patent: March 26, 2024
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 11865126
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: June 15, 2023
    Date of Patent: January 9, 2024
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Megan Croal, Hans Åke Eriksson, George Goldsmith, Molly Tabitha Hickey, Shaun Hurley, Ekaterina Malievskaia, Lindsey Marwood, Drummond E-Wen Joe Mcculloch, Laurie Emma Medhurst, Nathan Poulsen, Aslihan Selimbeyoglu, Anaïs Soula, Amanda Tan Shuxiang, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde, Stephen Wright
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11851451
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: November 21, 2022
    Date of Patent: December 26, 2023
    Assignee: COMPASS PATHFINDER LIMITED
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20230330117
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: June 15, 2023
    Publication date: October 19, 2023
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Åke ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anaïs SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 11738035
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: December 8, 2022
    Date of Patent: August 29, 2023
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Megan Croal, Hans Åke Eriksson, George Goldsmith, Molly Tabitha Hickey, Shaun Hurley, Ekaterina Malievskaia, Lindsey Marwood, Drummond E-Wen Joe McCulloch, Laurie Emma Medhurst, Nathan Poulsen, Aslihan Selimbeyoglu, Anaïs Soula, Amanda Tan Shuxiang, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde, Stephen Wright
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20230250115
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: April 17, 2023
    Publication date: August 10, 2023
    Applicants: Compass Pathfinder Limited, Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20230119714
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: November 21, 2022
    Publication date: April 20, 2023
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20230124137
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: December 8, 2022
    Publication date: April 20, 2023
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Åke ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anaïs SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11629159
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: April 18, 2023
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 11564935
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: January 31, 2023
    Assignee: COMPASS Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Megan Croal, Hans Åke Eriksson, George Goldsmith, Molly Tabitha Hickey, Shaun Hurley, Ekaterina Malievskaia, Lindsey Marwood, Drummond E-Wen Joe McCulloch, Laurie Emma Medhurst, Nathan Poulsen, Aslihan Selimbeyoglu, Anaïs Soula, Amanda Tan Shuxiang, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde, Stephen Wright
  • TREATMENT OF DEPRESSION AND OTHER VARIOUS DISORDERS WITH PSILOCYBIN
    Publication number: 20230023092
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat depression, neurocognitive disorders, autism spectrum disorder, and/or attention-deficit/hyperactivity disorder.
    Type: Application
    Filed: April 17, 2020
    Publication date: January 26, 2023
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Ake ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anais SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • METHODS FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20230000883
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: April 17, 2020
    Publication date: January 5, 2023
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Ake ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anais SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20220402949
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: August 11, 2022
    Publication date: December 22, 2022
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS