Abstract: Systems, methods, and compositions for identifying genomic variants and methylation analysis, including synthetic polynucleotide libraries, are provided. The synthetic polynucleotide libraries may comprise a plurality of polynucleotides. The polynucleotides may comprise sequences corresponding to a genetic abnormality in a genome. The stoichiometry of each of the plurality of polynucleotides is controlled. Systems, methods, and compositions described herein may include standards for determining the analytical sensitivity and/or accuracy of instruments configured to measure nucleic acid variant frequencies. Standards may comprise RNA-fusions and/or CNV mutations related to cancer.

Abstract: A sensor is configured to receive an input associated with a human present in a physical space in which a device is deployed. A physical circuit path is configured to electrically couple an output signal generated by the sensor to a premises automation system processing component. A physical privacy switch is configured to have a first position and a second position, wherein the physical privacy switch connects the physical circuit path when in the first position and interrupts the physical circuit path when in the second position.

Abstract: For each of a plurality of subsystems comprising a premises automation solution a corresponding current controlled state information is stored. Stored state information associated with the plurality of subsystems is used to generate and provide as output a recommendation to perform a recommended operation with respect to one or more of said subsystems.

Abstract: A device, comprises a microphone and a communication interface configured to send to a premises automation control core audio input received via the microphone. The premises automation control core is configured to determine, based at least in part on the audio input, a premises automation context associated with the device and send to the device via the communication interface a context data indicating the determined context. The devices also comprises a visual display device, a physical input device, and a processor coupled to the visual display device and the communication interface. The processor is configured to receive the context data and cause the visual display device to provide a visual display associated with the context data.

Abstract: An audio input associated with a human utterance received at the audio input device is received from a respective one of a plurality of audio input devices. Each of the plurality of audio input devices is located in a corresponding physical location within the premises. The audio input is mapped to an intent. An audible verbal response associated with the intent is provided as audio output via a selected one or more of a plurality of audio output devices. Each of the plurality of audio output devices is located in an associated physical location within the premises.

Abstract: One or more network communications to discover one or more controllable devices on a network with which a premises automation system is associated is sent automatically. A set of one or more controllable devices on the network is determined based at least in part on a response received from said one or more network communications. An assigned name that is unique within the premises automation system is assigned automatically to each of said set of one or more controllable devices.

Abstract: A rack for an auger is disclosed. The rack can have a body that is elongate along a longitudinal axis. A first mounting portion can extend from the body. The first mounting portion can defines a first receptacle that is configured to receive a portion of a shaft of the auger. Second and third mounting portions can be longitudinally spaced from the first receptacle. The second and third mounting portions can define second and third receptacles that are configured to receive respective portions of a handle of the auger. The second and third receptacles can be laterally spaced relative to each other along a transverse axis. A first retaining element can be configured to engage the auger to inhibit movement of the auger relative to the rack.

Abstract: A power module is configured to accept power from a cable, wherein the power module may be inserted into a standard wall cavity via a small hole. A processor module coupled to the power module comprises a processor and is configured to accept power from the cable for the processor, wherein the processor module may be inserted into the standard wall cavity via the small hole. A sensor module coupled to the processor module, comprises a sensor and is configured to accept input from the sensor for the processor, wherein the sensor module may be inserted into the small hole.

Abstract: The disclosure provides a synthetic standard which includes polynucleotides (e.g., DNA or RNA) containing multiple clinically important germline and somatic variants. These materials are utilized to calibrate, evaluate, and/or validate the performance of polynucleotide-based genetic analysis assays, such as NGS assays. In one aspect the disclosure provides a method for validating assay performance including generating synthetic variant DNA fragments comprising variants with known allele frequencies, wherein the fragments comprise a molecular tag; combining the synthetic variant DNA with wild-type DNA to create test samples; preparing one or more dilutions of the test samples; performing an assay of interest on the one or more dilutions of test samples; and comparing the outcome of the assay with the test samples with known allele frequencies of interest, thereby validating the performance of the assay.

Abstract: Particular embodiments described herein provide for an electronic device that can receive, at a rating system, a request for a data rating of data, determine a rating type for the data, receiving rating logic for the rating type, and rate the data using the rating logic. The rating logic for the rating type is included in a dedicated rating database. Also, the rating logic may separate from the rating system and the rating logic can be updated without having to update the rating system.

Abstract: A computer implemented method for extracting meaningful text from a document of unknown or unspecified format. In a particular embodiment, the method includes reading the document, thereby to extract raw encoded text, analysing the raw encoded text, thereby to identify one or more text chunks, and for a given chunk, performing compression identification analysis to determine whether compression is likely. The method can further include performing a decompression process, performing an encoding identification process thereby to identify a likely character encoding protocol, and converting the chunk using the identified likely character encoding protocol, thereby to output the chunk as readable text.

Abstract: A computer implemented method for extracting meaningful text from a document of unknown or unspecified format. In a particular embodiment, the method includes reading the document, thereby to extract raw encoded text, analysing the raw encoded text, thereby to identify one or more text chunks, and for a given chunk, performing compression identification analysis to determine whether compression is likely and, in the event that compression. The method can further include performing a decompression process, performing an encoding identification process thereby to identify a likely character encoding protocol, and converting the chunk using the identified likely character encoding protocol, thereby to output the chunk as readable text.

Abstract: Apparatus for making a reinforced absorbent member includes a forming chamber adapted to contain a fluent fibrous material. A forming surface is moveable within the forming chamber along an arcuate path generally from an entrance of the forming chamber to an exit thereof. The forming surface is adapted to collect fibrous material thereon to form the absorbent member. A source of reinforcing web is disposed generally exterior of the forming chamber. The forming chamber has an opening through which the reinforcing web is received into the forming chamber for subsequent conveyance within the forming chamber toward the forming surface. The opening is disposed downstream of the forming chamber entrance generally in the direction of movement of the forming surface along the path.

Abstract: Apparatus for making a reinforced fibrous absorbent member includes a forming chamber adapted to receive a fluent fibrous material and a forming surface moveable within the forming chamber and adapted to collect fibrous material to form the absorbent member. A source of reinforcing web is disposed exteriorly of the forming chamber. A delivery tube has an inlet end open to the forming chamber exterior, a discharge end open to the forming chamber interior, and a central passage extending between the inlet end and the discharge end. At least a portion of the delivery tube adjacent the discharge end extends within the forming chamber interior. The delivery tube is arranged for receiving the reinforcing web from the source of reinforcing web into the central passage of the tube at the inlet end and for guiding the web to the discharge end for conveyance within the forming chamber toward the forming surface.