Abstract: Presenting first drawer area on a first display device in an instrument panel of a vehicle, the first drawer area presented in an extended state; presenting second drawer area on a second display device in the instrument panel of the vehicle, the second drawer area presented in a retracted state; receiving first transition command regarding the first and second drawer areas; and in response to receiving the first transition command: presenting the first drawer area in the retracted state on the first display device, wherein the first content is not visible in the first drawer area in the retracted state; and presenting the second drawer area in the extended state on the second display device, wherein the first content of the first application is visible in the second drawer area.

Abstract: A system for harvesting solar energy on a spacecraft includes a stiff substrate layer and a working layer disposed on the substrate layer to provide at least one of a photovoltaic or a reflective function. In a first operational state, the substrate layer is arranged as a tape spring to store potential energy which causes the substrate layer to uncoil and provide, in a second operational state, a photovoltaic module and/or a solar concentrator.

Abstract: A pulse transit time is measured non-invasively and used to calculate a blood pressure value. A method of determining one or more blood pressure values includes propagating an alternating drive current through a thorax of a subject via electrodes located on a wrist-worn device. Resulting voltage levels of the subject are sensed by the wrist-worn device. The voltage levels are processed to detect when a volume of blood is ejected from the left ventricle. Output from a pulse arrival sensor coupled to the wrist-worn device is processed to detect when a blood pressure pulse generated by ejection of the volume of blood from the left ventricle arrives at the wrist. A pulse transit time (PTT) for transit of the blood pressure pulse from the left ventricle to the wrist is calculated. One or more blood pressure values for the subject are determined based on the PTT.

Abstract: In accordance with a first aspect of the present disclosure, a control system is provided for controlling electronic devices, the control system comprising: an ultra-wideband communication unit configured to receive ultra-wideband signals from the electronic devices, and a processing unit configured to select a specific electronic device among said electronic devices for further communication, wherein the processing unit is configured to select said specific electronic device using an angle of arrival of the ultra-wideband signals received from the electronic devices. In accordance with a second aspect of the present disclosure, a corresponding control method for controlling electronic devices is conceived. In accordance with a third aspect of the present disclosure, a computer program is provided, comprising executable instructions that, when executed by a control system for controlling electronic devices, cause said control system to carry out or control a method of the kind set forth.

Abstract: The application discloses methods and compositions for inhibiting functions associated with vascular endothelial growth factor-A (VEGF-A). The methods and compositions may involve the use of pan-variant specific aptamers for binding to VEGF-A, and preventing or reducing association of VEGF-A with Flt-1, KDR, or Nrp-1. The methods and compositions may include one or more aptamers that bind to receptor binding face of VEGF-A. The methods and compositions may include one or more aptamers that bind to a receptor binding domain of VEGF-A. The application further provides anti-VEGF-A aptamers for the treatment of ocular diseases or disorders. In some cases, the anti-VEGF-A aptamers may have a stem-loop secondary structure.

Abstract: A blood pressure cuff includes a support band that is selectively reconfigured between a flexible standby configuration and a measurement configuration. A blood pressure cuff includes an inflatable bladder, a support band, and a control unit. The support band is attached to and surrounds the inflatable bladder. The support band is reconfigurable, in response to an input from the control unit, from a standby configuration for between blood pressure measurements to a measurement configuration for constraining the inflatable bladder while the inflatable bladder is in an inflated state during a blood pressure measurement. The control unit includes a bladder pump for inflation of the inflatable bladder during a blood pressure measurement and controls the selective reconfiguration of the support band.

Abstract: In accordance with a first aspect of the present disclosure, a control system is provided for controlling electronic devices, the control system comprising: an ultra-wideband communication unit configured to receive ultra-wideband signals from the electronic devices, and a processing unit configured to select a specific electronic device among said electronic devices for further communication, wherein the processing unit is configured to select said specific electronic device using an angle of arrival of the ultra-wideband signals received from the electronic devices. In accordance with a second aspect of the present disclosure, a corresponding control method for controlling electronic devices is conceived. In accordance with a third aspect of the present disclosure, a computer program is provided, comprising executable instructions that, when executed by a control system for controlling electronic devices, cause said control system to carry out or control a method of the kind set forth.

Abstract: A method for facilitating a relative position determination is disclosed, comprising: a first radio frequency (RF) communication device measures a first angle of arrival, being an angle of arrival of a first RF signal received from a second RF communication device; the first RF communication device senses its orientation at a first time, resulting in a first orientation; the first RF communication device measures a second angle of arrival, being an angle of arrival of a second RF signal received from the second RF communication device; the first RF communication device senses its orientation at a second time, resulting in a second orientation; the relative position of the second RF communication device with respect to the first RF communication device is determined using a difference between the first angle of arrival and the second angle of arrival and a difference between the first orientation and the second orientation.

Abstract: The present disclosure generally relate s to blood pressure monitoring. In some embodiments, methods and devices for measuring a mean arterial pressure and/or for monitoring blood pressure changes of a user are provided. Blood pressure measured by one or more pressure sensors may be adjusted using one or more correction factors. The use of the one or more correction factors disclosed herein may allow for more compact, convenient, and/or accurate wearable blood pressure measurement devices and methods. In particular, wrist-worn devices may be provided which are less bulky than current devices and may facilitate more frequent and accurate blood pressure monitoring.

Abstract: Methods for estimating blood pressure values, and related blood pressure measurement systems, account for patient specific attributes. A method of estimating a blood pressure value of a patient includes receiving feature vector data corresponding to a pressure variation of a blood pressure cuff. The feature vector data is derived from physiological signals of the patient measured over the pressure variation of the blood pressure cuff. A first blood pressure value of the patient is estimated using a first algorithm that employs the feature vector data as input data.

Abstract: The present disclosure generally relate s to blood pressure monitoring. In some embodiments, methods and devices for measuring a mean arterial pressure and/or for monitoring blood pressure changes of a user are provided. Blood pressure measured by one or more pressure sensors may be adjusted using one or more correction factors. The use of the one or more correction factors disclosed herein may allow for more compact, convenient, and/or accurate wearable blood pressure measurement devices and methods. In particular, wrist-worn devices may be provided which are less bulky than current devices and may facilitate more frequent and accurate blood pressure monitoring.

Abstract: Methods and devices for obtaining a blood pressure measurement of a subject measure a transit time of a blood pulse of the subject. A method includes sensing, with a pulse ejection sensor of a wrist-worn device, ejection of blood from the left ventricle. Arrival of a resulting blood pressure pulse at the wrist is sensed via a pulse arrival sensor of the wrist-worn device. A transit time of the blood pressure pulse from the left ventricle to the wrist is determined. A relative blood pressure value of the subject is determined based on the transit time. A reference absolute blood pressure value associated with the relative blood pressure value is received. An absolute blood pressure value for the relative blood pressure value is determined based on the reference absolute blood pressure value and the relative blood pressure value.

Abstract: A pulse transit time is measured non-invasively and used to calculate a blood pressure value. A method of determining one or more blood pressure values includes propagating an alternating drive current through a thorax of a subject via electrodes located on a wrist-worn device. Resulting voltage levels of the subject are sensed by the wrist-worn device. The voltage levels are processed to detect when a volume of blood is ejected from the left ventricle. Output from a pulse arrival sensor coupled to the wrist-worn device is processed to detect when a blood pressure pulse generated by ejection of the volume of blood from the left ventricle arrives at the wrist. A pulse transit time (PTT) for transit of the blood pressure pulse from the left ventricle to the wrist is calculated. One or more blood pressure values for the subject are determined based on the PTT.

Abstract: Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device include a wrist-worn elongate band, at least four EKG or ICG electrodes coupled to the wrist-worn device for detecting a ventricular ejection of a heart, a photo-plethysmogram (PPG) sensor coupled to the wrist-worn device for detecting arrival of a blood pressure pulse at the user's wrist, and a controller configured to calculate a pulse transit time (PTT) for the blood pressure pulse. The controller calculates one or more blood pressure values for the user based on the PTT.

Abstract: The present invention provides non-invasive devices, methods, and systems for determining a pressure of blood within a cardiovascular system of a user, the cardiovascular system including a heart and the user having a wrist covered by skin. More particularly, the present invention discloses a variety of wrist-worn devices having a variety of sensors configured to non-invasively engage the skin on the wrist of the user for sensing a variety of user signals from the cardiovascular system of the user. Generally, approaches disclosed herein may passively track blood pressure values without any interaction required on the part of the user or may allow for on demand or point measurements of blood pressure values by having a user actively interact with the sensors of the wrist-worn device.

Abstract: In accordance with a first aspect of the present disclosure, a method for facilitating a relative position determination is conceived, comprising: a first radio frequency (RF) communication device measures a first angle of arrival, being an angle of arrival of a first RF signal received from a second RF communication device; the first RF communication device senses its orientation at a first time, resulting in a first orientation; the first RF communication device measures a second angle of arrival, being an angle of arrival of a second RF signal received from the second RF communication device; the first RF communication device senses its orientation at a second time, resulting in a second orientation; the relative position of the second RF communication device with respect to the first RF communication device is determined using a difference between the first angle of arrival and the second angle of arrival and a difference between the first orientation and the second orientation.

Abstract: The present invention generally relates to blood pressure monitoring. In some embodiments, methods and devices of measuring a mean arterial pressure are provided and/or monitoring blood pressure changes. A wrist-worn device may include a plurality of sensors backed by a plurality of actuators. Subsets of the plurality of sensors may be selectively actuateable against a wrist of a user using one or more of the plurality of actuators. A preferred sensor and location may be identified based on pressure signals received from each of the sensors. In some embodiments, devices may use a fluid bladder coupled with piezoelectric film sensors. A fluid bladder pressure sensor may be used to calibrate the piezoelectric film signal to provide a static and dynamic pressure reading. In yet another embodiment, a mean arterial pressure may be calculated by processing a swept pressure signal obtained as a sensor is swept through different heights.

Abstract: Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device includes an accelerometer, a photo-lethysmogram (PPG) or a pulse pressure sensor, and a controller. The PPG or the pulse pressure sensor coupled to the wrist-worn device for detecting an arrival of a blood pressure pulse at the user's wrist. The controller is configured to process output signals from the accelerometer to detect when the blood pressure pulse is propagated from the left ventricle of the user's heart, process a signal from the PPG or the pulse pressure sensor to detect when the blood pressure pulse arrives at the wrist, calculate a pulse transit time (PTT) for propagation of the blood pressure pulse from the left ventricle to the wrist, and generate one or more blood pressure values for the user based on the PTT.

Abstract: The present invention generally relates to blood pressure monitoring. In some embodiments, methods and devices of measuring a mean arterial pressure are provided and/or monitoring blood pressure changes. A wrist-worn device may include a plurality of sensors backed by a plurality of actuators. Subsets of the plurality of sensors may be selectively actuateable against a wrist of a user using one or more of the plurality of actuators. A preferred sensor and location may be identified based on pressure signals received from each of the sensors. In some embodiments, devices may use a fluid bladder coupled with piezoelectric film sensors. A fluid bladder pressure sensor may be used to calibrate the piezoelectric film signal to provide a static and dynamic pressure reading. In yet another embodiment, a mean arterial pressure may be calculated by processing a swept pressure signal obtained as a sensor is swept through different heights.

Abstract: The present invention provides non-invasive devices, methods, and systems for determining a pressure of blood within a cardiovascular system of a user, the cardiovascular system including a heart and the user having a wrist covered by skin. More particularly, the present invention discloses a variety of wrist-worn devices having a variety of sensors configured to non-invasively engage the skin on the wrist of the user for sensing a variety of user signals from the cardiovascular system of the user. Generally, approaches disclosed herein may passively track blood pressure values without any interaction required on the part of the user or may allow for on demand or point measurements of blood pressure values by having a user actively interact with the sensors of the wrist-worn device.