Patents by Inventor Derek Thomas

Derek Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9321840
    Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: April 26, 2016
    Assignees: UCB BIOPHARMA SPRL, BIOGEN MA INC.
    Inventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
  • Patent number: 9316108
    Abstract: Gas turbine engine frames are disclosed. An example gas turbine engine frame may include a generally annular outer casing disposed coaxially about a hub; a plurality of circumferentially spaced apart struts joined to the hub and the outer casing, individual struts extending radially outwardly from the hub to the outer casing; and a stiffening rail monolithically formed with the outer casing circumferentially between two of the struts. The stiffening rail may extend radially inward beyond the inner surface of the outer casing between the struts.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: April 19, 2016
    Assignee: General Electric Company
    Inventors: Courtland Earl Pegan, Jr., Kurt Thomas Hildebrand, Scott Patrick Ryczek, Derek Thomas Dreischarf
  • Publication number: 20160103923
    Abstract: A computer-implemented method and system are described for customizing content displayed to a user on a user device associated with the user. An example method may include receiving interaction data describing interactions by a user with one or more pages presented on a user device of the user, building a tag expression for the user based on the interaction data, the tag expression including a logical expression of tags and Boolean logic operators, and the tags being associated with page items. The method may also include generating a content page with a customized result customized to the user based on the tag expression.
    Type: Application
    Filed: January 28, 2015
    Publication date: April 14, 2016
    Inventors: Paul Derek Thomas, Young-Keun Andrew Lee
  • Publication number: 20160090862
    Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.
    Type: Application
    Filed: December 7, 2015
    Publication date: March 31, 2016
    Inventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
  • Publication number: 20160024812
    Abstract: An airform that can be inflated, for example, for facilitating construction of a structure is provided. The airform may include a first portion, a second portion, or multiple other portions, and reinforcement. The first portion may, for example, be configured to be disposed in a first orientation, such as vertically or in a radial profile, when the airform is inflated. The second portion transitioning from the first portion may be configured, for example, to assume an alternate shape and profile, such as a radial shape and profile, when the airform is inflated. The reinforcement may, for example, be provided at a portion of the airform that defines a transition from the first portion to the second portion.
    Type: Application
    Filed: July 25, 2014
    Publication date: January 28, 2016
    Inventors: Andrew John South, Randy John South, Derek Thomas South, Joshua Eric South, Nathan Samuel South, Jonathan William South
  • Patent number: 9212566
    Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 15, 2015
    Assignee: General Electric Company
    Inventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
  • Publication number: 20150233584
    Abstract: A rack (10) for holding cookware (66) on a cooktop (13) has a support rod (12) which is mounted on the cooktop by rod support stands (14, 16), and a ring shaped support member (18, 60, 62, 64) for cookware removably connected to the support rod by clips (24,26). The ring shaped support member has a support leg (36) which is mounted on the cooktop and is connected to the ring shaped support member such that the ring shaped support member is held in an elevated position over a heating element (17) of the cooktop. The ring shaped support member defines an opening (34) through which a vessel portion of cookware may be located.
    Type: Application
    Filed: September 17, 2013
    Publication date: August 20, 2015
    Inventor: Derek Thomas Mooney
  • Publication number: 20150135726
    Abstract: A surface heat exchanger is provided which utilizes forward and aft brackets to retain the heat exchanger in position. The surface heat exchanger includes a plurality of core cooling channels as well as fins which are disposed for air flow through the gas turbine engine. The brackets include a low-friction wear material as well as an isolator sheet which provides some spring force on the heat exchanger.
    Type: Application
    Filed: November 18, 2013
    Publication date: May 21, 2015
    Applicant: Unison Industries, LLC
    Inventors: Walter Arthur Hundley, JR., Derek Thomas Dreischarf, Dattu G. V. Jonnalagadda, Mark Phillip Drake
  • Publication number: 20150132054
    Abstract: A system for use in limiting axial movement between a hanger and a fairing assembly within a turbine assembly is provided. The hanger includes an inner radial hanger bend portion that defines a hook channel therein. The fairing assembly includes an outer surface, a hook member extending from the outer surface to mate with the hook channel, and a circumferential groove defined in the outer surface such that at least a portion of the hanger bend portion is positioned between the circumferential groove and the hook member. The system includes a retention member sized for insertion into the circumferential groove, wherein the retention member is configured to extend from the circumferential groove and press against the hanger bend portion to facilitate maintaining the hook member within the hook channel.
    Type: Application
    Filed: April 26, 2013
    Publication date: May 14, 2015
    Inventors: Derek Thomas Dreischarf, Courtland Earl Pegan, JR., Scott Patrick Ryczek
  • Patent number: 9022494
    Abstract: A bottom mount refrigerator is provided with refrigerator components housed in a space adjacent the top of the fresh food compartment between a false ceiling and the top wall of the compartment. The top wall includes a stepped portion formed in the liner forming the compartment. The stepped portion is positioned near the top and front of the compartment, and it includes a section that is lower than the remainder of the top wall. The stepped portion includes a rear facing face in the interior of the compartment, and the false ceiling is positioned between the rear facing face and the back wall. The ceiling extends horizontal from the rear wall before angling upward to abut the face of the stepped portion. The false ceiling may also contain apertures to provide access to the components housed between the ceiling and the top wall.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 5, 2015
    Assignee: Whirlpool Corporation
    Inventors: Derek Thomas Lehman, Frank Weston Maglinger
  • Patent number: 8784823
    Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: July 22, 2014
    Assignees: Biogen Idec MA Inc., UCB Biopharma SPRL
    Inventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
  • Publication number: 20130336782
    Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 19, 2013
    Inventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
  • Publication number: 20130270946
    Abstract: There is provided a magnetic bearing drive circuit driven from a pair of Direct Current (DC) link voltage rails, said magnetic bearing drive circuit having at least one amplifier providing an output PWM drive signal for driving a magnetic bearing winding, said output PWM drive signal being provided to the magnetic bearing winding through a plurality of drive signal rails, said magnetic bearing drive circuit comprising a pair of voltage offset devices coupled to the DC link voltage rails and arranged to provide a pair of offset catcher voltage rails from the DC link voltage rails, and primary clamping means coupled between each off-set catcher voltage rail and a respective one of the drive signal rails.
    Type: Application
    Filed: December 15, 2011
    Publication date: October 17, 2013
    Inventor: Derek Thomas Wright
  • Publication number: 20130227930
    Abstract: Gas turbine engine frames are disclosed. An example gas turbine engine frame may include a generally annular outer casing disposed coaxially about a hub; a plurality of circumferentially spaced apart struts joined to the hub and the outer casing, individual struts extending radially outwardly from the hub to the outer casing; and a stiffening rail monolithically formed with the outer casing circumferentially between two of the struts. The stiffening rail may extend radially inward beyond the inner surface of the outer casing between the struts.
    Type: Application
    Filed: March 5, 2012
    Publication date: September 5, 2013
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Courtland Earl Pegan, JR., Kurt Thomas Hildebrand, Scott Patrick Ryczek, Derek Thomas Dreischarf
  • Patent number: 8293237
    Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: October 23, 2012
    Assignees: UCB Pharma, S.A., Biogen Idec MA Inc.
    Inventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
  • Patent number: 8246471
    Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: August 21, 2012
    Assignee: Disney Enterprises, Inc.
    Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
  • Publication number: 20120040754
    Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.
    Type: Application
    Filed: October 26, 2011
    Publication date: February 16, 2012
    Applicant: DISNEY ENTERPRISES, INC.
    Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
  • Patent number: 8088012
    Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: January 3, 2012
    Assignee: Disney Enterprises, Inc.
    Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
  • Patent number: 7993864
    Abstract: The present invention provides a homogeneous assay for identifying an antibody producing cell producing an antibody which binds to a selected antigen comprising: a) providing a population of antibody producing cells; b) incubating said population of antibody producing cells with a selected antigen and a labeled anti-antibody antibody, wherein said anti-antibody antibody is capable of distinguishing cells producing an antibody which binds to the selected antigen from those cells which do not; and c) identifying an antibody producing cell capable of producing an antibody which binds to the selected antigen.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: August 9, 2011
    Assignee: UCB Pharma S.A.
    Inventors: Derek Thomas Brown, Lisa Butler, Karen Dorothy Cromie, Meryn Ruth Griffiths, Alastair David Griffiths Lawson, Daniel John Lightwood
  • Patent number: 7977464
    Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF?. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF?.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: July 12, 2011
    Assignee: UCB Pharma S.A.
    Inventors: Diljeet Singh Athwal, Derek Thomas Brown, Andrew Neil Charles Weir, Andrew George Popplewell, Andrew Paul Chapman, David John King