Patents by Inventor Derek Thomas
Derek Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9321840Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.Type: GrantFiled: June 19, 2014Date of Patent: April 26, 2016Assignees: UCB BIOPHARMA SPRL, BIOGEN MA INC.Inventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
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Patent number: 9316108Abstract: Gas turbine engine frames are disclosed. An example gas turbine engine frame may include a generally annular outer casing disposed coaxially about a hub; a plurality of circumferentially spaced apart struts joined to the hub and the outer casing, individual struts extending radially outwardly from the hub to the outer casing; and a stiffening rail monolithically formed with the outer casing circumferentially between two of the struts. The stiffening rail may extend radially inward beyond the inner surface of the outer casing between the struts.Type: GrantFiled: March 5, 2012Date of Patent: April 19, 2016Assignee: General Electric CompanyInventors: Courtland Earl Pegan, Jr., Kurt Thomas Hildebrand, Scott Patrick Ryczek, Derek Thomas Dreischarf
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Publication number: 20160103923Abstract: A computer-implemented method and system are described for customizing content displayed to a user on a user device associated with the user. An example method may include receiving interaction data describing interactions by a user with one or more pages presented on a user device of the user, building a tag expression for the user based on the interaction data, the tag expression including a logical expression of tags and Boolean logic operators, and the tags being associated with page items. The method may also include generating a content page with a customized result customized to the user based on the tag expression.Type: ApplicationFiled: January 28, 2015Publication date: April 14, 2016Inventors: Paul Derek Thomas, Young-Keun Andrew Lee
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Publication number: 20160090862Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.Type: ApplicationFiled: December 7, 2015Publication date: March 31, 2016Inventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
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Publication number: 20160024812Abstract: An airform that can be inflated, for example, for facilitating construction of a structure is provided. The airform may include a first portion, a second portion, or multiple other portions, and reinforcement. The first portion may, for example, be configured to be disposed in a first orientation, such as vertically or in a radial profile, when the airform is inflated. The second portion transitioning from the first portion may be configured, for example, to assume an alternate shape and profile, such as a radial shape and profile, when the airform is inflated. The reinforcement may, for example, be provided at a portion of the airform that defines a transition from the first portion to the second portion.Type: ApplicationFiled: July 25, 2014Publication date: January 28, 2016Inventors: Andrew John South, Randy John South, Derek Thomas South, Joshua Eric South, Nathan Samuel South, Jonathan William South
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Patent number: 9212566Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.Type: GrantFiled: March 15, 2013Date of Patent: December 15, 2015Assignee: General Electric CompanyInventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
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Publication number: 20150233584Abstract: A rack (10) for holding cookware (66) on a cooktop (13) has a support rod (12) which is mounted on the cooktop by rod support stands (14, 16), and a ring shaped support member (18, 60, 62, 64) for cookware removably connected to the support rod by clips (24,26). The ring shaped support member has a support leg (36) which is mounted on the cooktop and is connected to the ring shaped support member such that the ring shaped support member is held in an elevated position over a heating element (17) of the cooktop. The ring shaped support member defines an opening (34) through which a vessel portion of cookware may be located.Type: ApplicationFiled: September 17, 2013Publication date: August 20, 2015Inventor: Derek Thomas Mooney
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Publication number: 20150135726Abstract: A surface heat exchanger is provided which utilizes forward and aft brackets to retain the heat exchanger in position. The surface heat exchanger includes a plurality of core cooling channels as well as fins which are disposed for air flow through the gas turbine engine. The brackets include a low-friction wear material as well as an isolator sheet which provides some spring force on the heat exchanger.Type: ApplicationFiled: November 18, 2013Publication date: May 21, 2015Applicant: Unison Industries, LLCInventors: Walter Arthur Hundley, JR., Derek Thomas Dreischarf, Dattu G. V. Jonnalagadda, Mark Phillip Drake
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Publication number: 20150132054Abstract: A system for use in limiting axial movement between a hanger and a fairing assembly within a turbine assembly is provided. The hanger includes an inner radial hanger bend portion that defines a hook channel therein. The fairing assembly includes an outer surface, a hook member extending from the outer surface to mate with the hook channel, and a circumferential groove defined in the outer surface such that at least a portion of the hanger bend portion is positioned between the circumferential groove and the hook member. The system includes a retention member sized for insertion into the circumferential groove, wherein the retention member is configured to extend from the circumferential groove and press against the hanger bend portion to facilitate maintaining the hook member within the hook channel.Type: ApplicationFiled: April 26, 2013Publication date: May 14, 2015Inventors: Derek Thomas Dreischarf, Courtland Earl Pegan, JR., Scott Patrick Ryczek
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Patent number: 9022494Abstract: A bottom mount refrigerator is provided with refrigerator components housed in a space adjacent the top of the fresh food compartment between a false ceiling and the top wall of the compartment. The top wall includes a stepped portion formed in the liner forming the compartment. The stepped portion is positioned near the top and front of the compartment, and it includes a section that is lower than the remainder of the top wall. The stepped portion includes a rear facing face in the interior of the compartment, and the false ceiling is positioned between the rear facing face and the back wall. The ceiling extends horizontal from the rear wall before angling upward to abut the face of the stepped portion. The false ceiling may also contain apertures to provide access to the components housed between the ceiling and the top wall.Type: GrantFiled: September 14, 2012Date of Patent: May 5, 2015Assignee: Whirlpool CorporationInventors: Derek Thomas Lehman, Frank Weston Maglinger
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Patent number: 8784823Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.Type: GrantFiled: October 22, 2012Date of Patent: July 22, 2014Assignees: Biogen Idec MA Inc., UCB Biopharma SPRLInventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
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Publication number: 20130336782Abstract: A fairing for a turbine engine strut includes: inner and outer bands; a vane extending between the bands; the fairing is split along a generally transverse plane passing through the bands and the vane, defining nose and tail pieces; wherein the vane is defined by spaced-apart sidewalls extending between a leading edge and a trailing edge, each sidewall split into forward and aft portions by the transverse plane; wherein each sidewall portion carries a radially-inwardly extending post, the posts positioned such that pairs of the posts lie adjacent to each other when the nose piece and tail piece are assembled, wherein each pair of adjacent posts includes at least two non-parallel faces; and a pair of slotted buckles, wherein each slotted buckle surrounds and clamps together a pair of the posts, wherein each pair of adjacent posts contacts a slot of the corresponding buckle in a tripod contact configuration.Type: ApplicationFiled: March 15, 2013Publication date: December 19, 2013Inventors: Scott Patrick Ryczek, Derek Thomas Dreischarf
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Publication number: 20130270946Abstract: There is provided a magnetic bearing drive circuit driven from a pair of Direct Current (DC) link voltage rails, said magnetic bearing drive circuit having at least one amplifier providing an output PWM drive signal for driving a magnetic bearing winding, said output PWM drive signal being provided to the magnetic bearing winding through a plurality of drive signal rails, said magnetic bearing drive circuit comprising a pair of voltage offset devices coupled to the DC link voltage rails and arranged to provide a pair of offset catcher voltage rails from the DC link voltage rails, and primary clamping means coupled between each off-set catcher voltage rail and a respective one of the drive signal rails.Type: ApplicationFiled: December 15, 2011Publication date: October 17, 2013Inventor: Derek Thomas Wright
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Publication number: 20130227930Abstract: Gas turbine engine frames are disclosed. An example gas turbine engine frame may include a generally annular outer casing disposed coaxially about a hub; a plurality of circumferentially spaced apart struts joined to the hub and the outer casing, individual struts extending radially outwardly from the hub to the outer casing; and a stiffening rail monolithically formed with the outer casing circumferentially between two of the struts. The stiffening rail may extend radially inward beyond the inner surface of the outer casing between the struts.Type: ApplicationFiled: March 5, 2012Publication date: September 5, 2013Applicant: GENERAL ELECTRIC COMPANYInventors: Courtland Earl Pegan, JR., Kurt Thomas Hildebrand, Scott Patrick Ryczek, Derek Thomas Dreischarf
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Patent number: 8293237Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.Type: GrantFiled: March 21, 2008Date of Patent: October 23, 2012Assignees: UCB Pharma, S.A., Biogen Idec MA Inc.Inventors: Linda C. Burkly, Janine L. Ferrant-Orgettas, Ellen A. Garber, Yen-Ming Hsu, Lihe Su, Frederick R. Taylor, Ralph Adams, Derek Thomas Brown, Andrew George Popplewell, Martyn Kim Robinson, Anthony Shock, Kerry Louise Tyson
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Patent number: 8246471Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.Type: GrantFiled: October 26, 2011Date of Patent: August 21, 2012Assignee: Disney Enterprises, Inc.Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
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Publication number: 20120040754Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.Type: ApplicationFiled: October 26, 2011Publication date: February 16, 2012Applicant: DISNEY ENTERPRISES, INC.Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
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Patent number: 8088012Abstract: There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.Type: GrantFiled: January 29, 2009Date of Patent: January 3, 2012Assignee: Disney Enterprises, Inc.Inventors: Derek Thomas Dutilly, Michael Jacob, Amy Kalson
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Patent number: 7993864Abstract: The present invention provides a homogeneous assay for identifying an antibody producing cell producing an antibody which binds to a selected antigen comprising: a) providing a population of antibody producing cells; b) incubating said population of antibody producing cells with a selected antigen and a labeled anti-antibody antibody, wherein said anti-antibody antibody is capable of distinguishing cells producing an antibody which binds to the selected antigen from those cells which do not; and c) identifying an antibody producing cell capable of producing an antibody which binds to the selected antigen.Type: GrantFiled: December 1, 2003Date of Patent: August 9, 2011Assignee: UCB Pharma S.A.Inventors: Derek Thomas Brown, Lisa Butler, Karen Dorothy Cromie, Meryn Ruth Griffiths, Alastair David Griffiths Lawson, Daniel John Lightwood
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Patent number: 7977464Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF?. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF?.Type: GrantFiled: June 18, 2008Date of Patent: July 12, 2011Assignee: UCB Pharma S.A.Inventors: Diljeet Singh Athwal, Derek Thomas Brown, Andrew Neil Charles Weir, Andrew George Popplewell, Andrew Paul Chapman, David John King