Patents by Inventor Derek Toomre

Derek Toomre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Super-resolution imaging compositions and methods using same
    Patent number: 10087199
    Abstract: The invention provides compositions that may be used for imaging intracellular structures. The invention further provides methods of imaging intracellular structures. In certain embodiments, the compositions of the invention include trans-cyclooctene-containing ceramide lipids and tetrazine-containing rhodamine-related dyes.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: October 2, 2018
    Assignee: Yale University
    Inventors: Roman Erdmann, Alanna Schepartz Shrader, Derek Toomre
  • Novel Super-Resolution Imaging Compositions and Methods Using Same
    Publication number: 20160115180
    Abstract: The invention provides compositions that may be used for imaging intracellular structures. The invention further provides methods of imaging intracellular structures. In certain embodiments, the compositions of the invention include trans-cyclooctene-containing ceramide lipids and tetrazine-containing rhodamine-related dyes.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 28, 2016
    Inventors: Roman ERDMANN, Alanna Schepartz SHRADER, Derek TOOMRE
  • Optical system for illumination of an evanescent field
    Patent number: 7835076
    Abstract: A system of optics used to provide illumination through an objective at a precise inclination angle and with uniform intensity across an illuminated field. The system provides annular illumination with a continuously variable diameter at the back aperture of an objective. The resultant illumination field at the imaging plane of the objective includes rays with a single inclination angle with respect to the optical axis of the objective. This incidence angle is determined by the position of an axicon lens. The imaging plane is illuminated from 360 degrees rotation about optical axis of the objective.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 16, 2010
    Assignee: Yale University
    Inventors: Robert Roorda, Derek Toomre
  • Optical System for Illumination of an Evanescent Field
    Publication number: 20090168159
    Abstract: A system of optics used to provide illumination through an objective at a precise inclination angle and with uniform intensity across an illuminated field. The system provides annular illumination with a continuously variable diameter at the back aperture of an objective. The resultant illumination field at the imaging plane of the objective includes rays with a single inclination angle with respect to the optical axis of the objective. This incidence angle is determined by the position of an axicon lens. The imaging plane is illuminated from 360 degrees rotation about optical axis of the objective.
    Type: Application
    Filed: October 26, 2006
    Publication date: July 2, 2009
    Inventors: Robert Roorda, Derek Toomre