Patents by Inventor Derek Turner
Derek Turner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9873692Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: GrantFiled: March 15, 2017Date of Patent: January 23, 2018Assignee: THERAVANCE BIOPHARMA R&D IP, LLCInventors: Daniel Marquess, Paul R. Fatheree, S. Derek Turner, Daniel D. Long, Seok-Ki Choi, Adam A. Goldblum
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Publication number: 20180003393Abstract: A griddle and gas burner range, including: a griddle having an electric heating element, and a griddle plate that is disposed over the electric heating element; at least one open top gas burner disposed adjacent to the griddle; and a heat barrier installed between the griddle and the at least one open top gas burner, so as to block the escape of heat from the griddle and into an area of the at least one open top gas burner during operation of the griddle.Type: ApplicationFiled: June 30, 2016Publication date: January 4, 2018Inventors: Ben Braden, Charlie Hanna, Brian Silva, Derek Turner
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Publication number: 20170334901Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: March 15, 2017Publication date: November 23, 2017Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: DANIEL MARQUESS, PAUL R. FATHEREE, S. DEREK TURNER, DANIEL D. LONG, SEOK-KI CHOI, ADAM A. GOLDBLUM
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Patent number: 9809894Abstract: In a process for anodizing a metal object (12), the metal object (12) is contacted with an anodizing electrolyte (32), and is first pre-anodized so as to grow a thin oxide film on the surface. The microscopic surface area is then deduced from electrical measurements either during pre-anodizing or on the pre-anodized surface. The metal object (12) can then be anodized. This is applicable when treating an implant to provide a surface that has the ability to incorporate biocidal material such as silver ions. The pre-anodizing uses a low voltage, for example no more than 2. V, and may take less than 120 seconds.Type: GrantFiled: January 13, 2012Date of Patent: November 7, 2017Assignee: Accentus Medical LimitedInventor: Andrew Derek Turner
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Patent number: 9738980Abstract: Metal objects are treated by anodizing (P, SE) the metal object in contact with an acidic solution, and then subjecting the anodized metal object to a reversed voltage (VR). The anodizing is performed in two stages, firstly to passivate (P) with the formation of a surface layer, and secondly to form pits in this surface layer (SE). The second stage (SE) of anodizing is performed at a lower voltage than the first stage (P). After the reversed voltage step (VR) the metal object is then contacted with a biocidal metal-containing solution. Biocidal metal is absorbed into the surface of the metal object, resulting in improved biocidal properties. The lower voltage of the second stage anodizing (SE) results in reduced processing time.Type: GrantFiled: June 29, 2015Date of Patent: August 22, 2017Assignee: Accentus Medical LimitedInventors: James Timothy Shawcross, David Richard Lewis, Andrew Derek Turner
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Patent number: 9649410Abstract: A metal implant for use in a surgical procedure is provided with a surface layer that is integral with the metal substrate, and which incorporates a biocidal material. The surface layer may be grown from the metal substrate, by anodising, and the biocidal material incorporated in it by ion exchange. Alternatively the layer may be deposited by electroplating, followed by diffusion bonding so as to become integral with the metal substrate. In either case, silver is a suitable biocidal material; and both the release rate and the quantity of biocidal material should be low to avoid toxic effects on body cells. Electropolishing the surface before formation of the surface layer is also beneficial, and this may be achieved by electropolishing.Type: GrantFiled: December 23, 2014Date of Patent: May 16, 2017Assignee: Accentus Medical LimitedInventors: Martin Edward Lee Pickford, Andrew Derek Turner
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Patent number: 9630960Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: GrantFiled: April 27, 2016Date of Patent: April 25, 2017Assignee: Theravance Biopharma R&D IP, LLCInventors: Daniel Marquess, Paul R. Fatheree, S. Derek Turner, Daniel D. Long, Seok-Ki Choi, Adam A. Goldblum
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Publication number: 20160376264Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: April 27, 2016Publication date: December 29, 2016Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: DANIEL MARQUESS, PAUL R. FATHEREE, S. DEREK TURNER, DANIEL D. LONG, SEOK-KI CHOI, ADAM A. GOLDBLUM
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Publication number: 20160316553Abstract: A printed circuit board assembly (PCBA) controls an electrically-initiated device (EID) in an electric field. The PCBA includes a conductive layer, a dielectric layer, and a transconductive layer (TCL). The conductive layer of the PCBA designated protected areas. An electrical current with a predetermined current density is impressed in the conductive layer when the PCBA is in the electric field. The TCL is a nickel-metal composite metamaterial positioned between the conductive and dielectric layers and configured to change in shape or thickness in the electric field such that the impressed current is steered away from the conductive layer and into the dielectric layer to prevent premature activation of the EID. A system includes an outer housing, power supply, an EID such as a sonobuoy or medical device, and the PCBA, all of which are encapsulated in the housing. A method is also disclosed for manufacturing the PCBA.Type: ApplicationFiled: July 6, 2016Publication date: October 27, 2016Applicant: Sparton CorporationInventors: Lendon L. Bendix, Derek Turner
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Patent number: 9402840Abstract: The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.Type: GrantFiled: August 3, 2015Date of Patent: August 2, 2016Assignee: Theravance Biopharma R&D IP, LLCInventors: Paul R. Fatheree, S. Derek Turner, Adam A. Goldblum, Robert S. Chao, Daniel Genov
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Patent number: 9393349Abstract: A metal implant for use in a surgical procedure is provided with a surface layer that is integral with the metal substrate, and which incorporates a biocidal material. The surface layer may be grown from the metal substrate, by anodizing, and the biocidal material incorporated in it by ion exchange. Alternatively the layer may be deposited by electroplating, followed by diffusion bonding so as to become integral with the metal substrate. In either case, silver is a suitable biocidal material; and both the release rate and the quantity of biocidal material should be low to avoid toxic effects on body cells. Electropolishing the surface before formation of the surface layer is also beneficial, and this may be achieved by electropolishing.Type: GrantFiled: August 11, 2009Date of Patent: July 19, 2016Assignee: Accentus Medical LimitedInventors: Martin Edward Lee Pickford, Andrew Derek Turner
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Patent number: 9353106Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: GrantFiled: January 13, 2015Date of Patent: May 31, 2016Assignee: Theravance Biopharma R&D IP, LLCInventors: Daniel Marquess, Paul R. Fatheree, S. Derek Turner, Daniel D. Long, Seok-Ki Choi, Adam A. Goldblum
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Publication number: 20160095849Abstract: The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.Type: ApplicationFiled: August 3, 2015Publication date: April 7, 2016Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: Paul R. Fatheree, S. Derek Turner, Adam A. Goldblum, Robert S. Chao, Daniel Genov
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Publication number: 20150299865Abstract: Metal objects are treated by anodising (P, SE) the metal object in contact with an acidic solution, and then subjecting the anodised metal object to a reversed voltage (VR). The anodising is performed in two stages, firstly to passivate (P) with the formation of a surface layer, and secondly to form pits in this surface layer (SE). The second stage (SE) of anodising is performed at a lower voltage than the first stage (P). After the reversed voltage step (VR) the metal object is then contacted with a biocidal metal-containing solution. Biocidal metal is absorbed into the surface of the metal object, resulting in improved biocidal properties. The lower voltage of the second stage anodising (SE) results in reduced processing time.Type: ApplicationFiled: June 29, 2015Publication date: October 22, 2015Applicant: ACCENTUS MEDICAL LIMITEDInventors: James Timothy Shawcross, David Richard Lewis, Andrew Derek Turner
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Publication number: 20150291580Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: January 13, 2015Publication date: October 15, 2015Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: DANIEL MARQUESS, PAUL R. FATHEREE, S. DEREK TURNER, DANIEL D. LONG, SEOK-KI CHOI, ADAM A. GOLDBLUM
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Patent number: 9126994Abstract: The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.Type: GrantFiled: January 8, 2014Date of Patent: September 8, 2015Assignee: Theravance Biopharma R&D IP, LLCInventors: Paul R. Fatheree, S. Derek Turner, Adam A. Goldblum, Robert S. Chao, Daniel Genov
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Publication number: 20150245548Abstract: A printed circuit board assembly (PCBA) controls an electrically-initiated device (EID) in an electric field. The PCBA includes a conductive layer, a dielectric layer, and a trans-conductive layer (TCL). The PCBA has one or more designated protected areas. An electrical current with a predetermined current density is present in the conductive layer when the PCBA is placed in the electric field. The TCL is constructed of a nickel-metal composite metamaterial positioned between the conductive and dielectric layers. The TCL has a variable geometry with respect to at least one of the thickness, width, and length of the PCBA, and compresses in proportion to an energy level of the electric field to direct the electrical current away from the designated protected area(s). A system includes a housing, a power supply, an EID such as a sonobuoy or medical device, and the PCBA, all of which are encapsulated in the housing.Type: ApplicationFiled: February 26, 2014Publication date: August 27, 2015Applicant: Sparton CorporationInventors: Lendon L. Bendix, Derek Turner
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Patent number: 9096943Abstract: Metal objects are treated by anodising (P, SE) the metal object in contact with an acidic solution, and then subjecting the anodised metal object to a reversed voltage (VR). The anodising is performed in two stages, firstly to passivate (P) with the formation of a surface layer, and secondly to form pits in this surface layer (SE). The second stage (SE) of anodising is performed at a lower voltage than the first stage (P). After the reversed voltage step (VR) the metal object is then contacted with a biocidal metal-containing solution. Biocidal metal is absorbed into the surface of the metal object, resulting in improved biocidal properties. The lower voltage of the second stage anodising (SE) results in reduced processing time.Type: GrantFiled: March 29, 2010Date of Patent: August 4, 2015Assignee: Accentus Medical LimitedInventors: James Timothy Shawcross, David Richard Lewis, Andrew Derek Turner
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Patent number: 9080250Abstract: A metal object is treated to form an integral surface layer by: (a) immersing the metal object in an anodising electrolyte, and passivating the metal to form an anodised layer on the metal object; (b) continuing the application of a potential to modify the surface layer; (c) then treating the metal object with a chemical reducing agent so a hydrous metal oxide is formed; and (d) then contacting the metal object with a solution containing a biocidal material so as to incorporate biocidal material into the surface layer.Type: GrantFiled: March 30, 2010Date of Patent: July 14, 2015Assignee: Accentus Medical LimitedInventor: Andrew Derek Turner
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Publication number: 20150110844Abstract: A metal implant for use in a surgical procedure is provided with a surface layer that is integral with the metal substrate, and which incorporates a biocidal material. The surface layer may be grown from the metal substrate, by anodising, and the biocidal material incorporated in it by ion exchange. Alternatively the layer may be deposited by electroplating, followed by diffusion bonding so as to become integral with the metal substrate. In either case, silver is a suitable biocidal material; and both the release rate and the quantity of biocidal material should be low to avoid toxic effects on body cells. Electropolishing the surface before formation of the surface layer is also beneficial, and this may be achieved by electropolishing.Type: ApplicationFiled: December 23, 2014Publication date: April 23, 2015Applicant: Acentus Medical LimitedInventors: Martin Edward Lee Pickford, Andrew Derek Turner