Patents by Inventor Derick H. Lau

Derick H. Lau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for screening combinational bead library; ligands for cancer cells
    Patent number: 7262269
    Abstract: The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of epithelial and non-epithelial cells. Cells are incubated with a compound bead library for 24 to 72-hours, allowing them to attach and grow on the beads. Those beads with cells growing are removed, and the ligand on the bead is identified. Also provided are ligands specific for cancer cells.
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: August 28, 2007
    Assignee: The Regents of University of California
    Inventors: Kit S. Lam, Derick H. Lau
  • Method for screening combinatorial bead library; ligands for cancer cells
    Publication number: 20040096906
    Abstract: The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of epithelial and non-epithelial cells. Cells are incubated with a compound bead library for 24 to 72-hours, allowing them to attach and grow on the beads. Those beads with cells growing are removed, and the ligand on the bead is identified. Also provided are ligands specific for cancer cells.
    Type: Application
    Filed: October 8, 2003
    Publication date: May 20, 2004
    Inventors: Kit S. Lam, Derick H. Lau
  • Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells
    Patent number: 6670142
    Abstract: The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of epithelial cells. Cells are incubated with a compound bead library for 24 to 72-hours, allowing them to attach and grow on the beads. Those beads with cells growing are removed, and the ligand on the bead is identified. Also provided are ligands specific for epithelial cancer cells. The invention also includes a method of capturing epithelial cells from body fluids. In this method, beads are prepared with a known ligand specific for a particular type of cell and incubated for 24 to 72 hours with a sample of the body fluid being tested. Those cells attached to the beads are removed and identified.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: December 30, 2003
    Assignee: The Regents of the University of California
    Inventors: Derick H. Lau, Kit S. Lam
  • Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells
    Publication number: 20030170735
    Abstract: The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of epithelial cells. Cells are incubated with a compound bead library for 24 to 72-hours, allowing them to attach and grow on the beads. Those beads with cells growing are removed, and the ligand on the bead is identified. Also provided are ligands specific for epithelial cancer cells. The invention also includes a method of capturing epithelial cells from body fluids. In this method, beads are prepared with a known ligand specific for a particular type of cell and incubated for 24 to 72 hours with a sample of the body fluid being tested. Those cells attached to the beads are removed and identified.
    Type: Application
    Filed: October 26, 2001
    Publication date: September 11, 2003
    Inventors: Derick H. Lau, Kit S. Lam