Patents by Inventor Derrick BROKA

Derrick BROKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230372384
    Abstract: The present invention relates to a kit-of-parts comprising and a composition comprising a polyplex comprising a double stranded RNA (dsRNA) and a polymeric conjugate comprising a polyethyleneimine (PEI), one or more polyethylene glycol (PEG) moieties and one or more targeting moieties, and wherein each of said one or more targeting moieties is capable of 5 binding to PSMA; and at least one least one immune checkpoint modulator, wherein said at least one least one immune checkpoint modulator is capable of modulating an immune checkpoint protein. Further the invention relates to this composition or kit-of-parts for use in the treatment of cancer.
    Type: Application
    Filed: October 7, 2021
    Publication date: November 23, 2023
    Inventors: Esteban POMBO-VILLAR, Eric KITAS, Maya ZIGLER, Davor BAJIC, Babette SCHADE, Derrick BROKA
  • Publication number: 20220175814
    Abstract: The present invention relates to a kit-of-parts comprising and a composition comprising a polyplex comprising a double stranded RNA (dsRNA) and a polymeric conjugate comprising a polyethyleneimine (PEI), one or more polyethylene glycol (PEG) moieties and one or more targeting moieties, and wherein each of said one or more targeting moieties is capable of binding to a cancer antigen; and at least one antibody, wherein said at least one antibody is capable of modulating an immune checkpoint protein. Further the invention relates to this composition or kit-of-parts for use in the treatment of cancer.
    Type: Application
    Filed: April 3, 2020
    Publication date: June 9, 2022
    Inventors: Derrick BROKA, David COLECCHIA, Lucia D'AMICO, Eric KITAS, Alexander LEVITZKI, Esteban POMBO-VILLAR, Alexei SHIR, Maya ZIGLER, Davor BAJIC, Anita JARZEBINSKA