Patents by Inventor Derrick Gibbings

Derrick Gibbings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10851372
    Abstract: A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise: introducing into an exosome-producing cell a nucleic acid construct comprising the nucleic acid sequence of interest incorporated in a pre-miR-451 structural mimic, and allowing the cell to produce exosomes. Nucleic acid constructs, compositions, and uses thereof are also provided.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: December 1, 2020
    Assignee: University of Ottawa
    Inventors: Derrick Gibbings, James Andrew Taylor
  • Publication number: 20190093105
    Abstract: A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise: introducing into an exosome-producing cell a nucleic acid construct comprising the nucleic acid sequence of interest incorporated in a pre-miR-451 structural mimic, and allowing the cell to produce exosomes. Nucleic acid constructs, compositions, and uses thereof are also provided.
    Type: Application
    Filed: September 30, 2016
    Publication date: March 28, 2019
    Applicant: University of Ottawa
    Inventors: Derrick Gibbings, James Andrew Taylor
  • Publication number: 20110177054
    Abstract: The present invention relates to a method for determining the delivery rates and/or efficiency of a siRNA, miRNA or related molecule to target organs or cells, a kit and the use of proteins or lipids involved in the formation of the endolysosomal system for modulating the activity and/or the cell-to-cell transfer of RNA, small RNA, for example miRNA, siRNA and piRNA, mRNA or non-coding RNA. It finds many applications in particular in methods for identifying the target(s) of miRNA or siRNA therapeutics, in methods for determining the efficiency of a treatment with siRNA and/or miRNA therapeutics, in methods for determining the efficiency of a treatment with siRNA and/or miRNA therapeutics, and in methods for genotyping and/or characterizing the condition of a person, a tumor or a fetus.
    Type: Application
    Filed: June 5, 2009
    Publication date: July 21, 2011
    Inventors: Derrick Gibbings, Olivier Voinnet