Patents by Inventor Derrick James Dargan

Derrick James Dargan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Herpesvirus pre-(viral DNA replication) enveloped particles
    Patent number: 5994116
    Abstract: This invention is directed toward a new type of herpesvirus particle (e.g., HSV-1), herein designated pre-viral DNA replication enveloped particles (PREPS), and methods of preparing said particles. These particles are non-infectious and can be prepared reliably to a high ratio of HSV-1 PREPS to infectious virus of at least 10.sup.7 :1. PREPS can be produced under conditions wherein viral DNA replication is blocked through the use of suitable drugs (e.g., acyclovir [ACV]; cytosine-.beta.-D-arabinofuranoside [ara C]) or by using an HSV mutant defective in viral DNA synthesis.
    Type: Grant
    Filed: July 19, 1996
    Date of Patent: November 30, 1999
    Assignee: Medical Research Council
    Inventors: Derrick James Dargan, Arvind Hirabhai Patel, John Herbert Subak-Sharpe