Abstract: A portable compress device includes a main body, a power source, an electric means for generating a temperature gradient on a plurality of surfaces, a controller means coupled with the electric means and the power source, a thermal sensor device configured to be in proximity to a user's skin at a treatment area, and a plurality of pad attachment and detachment means for attaching and detaching a pad assembly to and from the plurality of surfaces, wherein the pad assembly is for moistened or dry application on the treatment area.