Patents by Inventor Derya SHIMSHEK

Derya SHIMSHEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREM2 STABILIZING ANTIBODIES
    Publication number: 20230167174
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Application
    Filed: September 23, 2022
    Publication date: June 1, 2023
    Inventors: Verena BRAND, Dominik FEUERBACH, Fabrizio GASPARINI, Nathalie GEORGE, Eveline SCHAADT, Derya SHIMSHEK, Honnappa SRINIVAS, Markus WALDHUBER, Rainer WILCKEN
  • TREM2 stabilizing antibodies
    Patent number: 11492402
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: November 8, 2022
    Assignee: NOVARTIS AG
    Inventors: Verena Brand, Dominik Feuerbach, Fabrizio Gasparini, Nathalie George, Eveline Schaadt, Derya Shimshek, Honnappa Srinivas, Markus Waldhuber, Rainer Wilcken
  • Oxazine derivative for use in the treatment or prevention of cerebral amyloid angiopathy
    Patent number: 10722518
    Abstract: The present invention relates to an oxazine derivative BACE-1 inhibitor and pharmaceutical compositions comprising such oxazine derivative for use in the treatment or prevention of cerebral amyloid angiopathy and, in particular, wherein the patient carries one or two copies of the ApoE4 allele.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: July 28, 2020
    Assignee: Novartis AG
    Inventors: Cristina Lopez-Lopez, Ulf Neumann, Derya Shimshek
  • TREM2 STABILIZING ANTIBODIES
    Publication number: 20200140545
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Application
    Filed: October 14, 2019
    Publication date: May 7, 2020
    Inventors: Verena BRAND, Dominik FEUERBACH, Fabrizio GASPARINI, Nathalie GEORGE, Eveline SCHAADT, Derya SHIMSHEK, Honnappa SRINIVAS, Markus WALDHUBER, Rainer WILCKEN
  • NEW METHODS FOR THE TREATMENT OF MULTIPLE SCLEROSIS
    Publication number: 20200093801
    Abstract: The present invention relates to methods of treating multiple sclerosis, amyotrophic lateral sclerosis (ALS) or Alzheimer's disease in a subject in need of treatment thereof by administering an effective amount of 4-(2-((1R,2R)-2-hydroxycyclohexylamino)benzothiazol-6-yloxy)-N-methylpicolinamide or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 26, 2018
    Publication date: March 26, 2020
    Inventor: Derya SHIMSHEK
  • OXAZINE DERIVATIVE FOR USE IN THE TREATMENT OR PREVENTION OF CEREBRAL AMYLOID ANGIOPATHY
    Publication number: 20180125853
    Abstract: The present invention relates to an oxazine derivative BACE-1 inhibitor and pharmaceutical compositions comprising such oxazine derivative for use in the treatment or prevention of cerebral amyloid angiopathy and, in particular, wherein the patient carries one or two copies of the ApoE4 allele.
    Type: Application
    Filed: October 11, 2017
    Publication date: May 10, 2018
    Inventors: Cristina LOPEZ-LOPEZ, Ulf NEUMANN, Derya SHIMSHEK