Patents by Inventor Desheng YU

Desheng YU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
    Patent number: 11555038
    Abstract: The present invention relates to a crystalline form of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide (Compound 1) for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease, such as an allergic disease, an autoimmune disease, an inflammatory disease, and a cancer.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: January 17, 2023
    Assignee: BEIGENE, LTD.
    Inventors: Yunhang Guo, Desheng Yu, Zhiwei Wang
  • BTK INHIBITORS WITH IMPROVED DUAL SELECTIVITY
    Publication number: 20220298163
    Abstract: Disclosed herein is a tri-substituted phenyl Btk inhibitors with improved dual selectivity, a method and a composition for inhibiting Btk and treating disease associated with undesirable Btk activity (Btk-related diseases).
    Type: Application
    Filed: May 31, 2022
    Publication date: September 22, 2022
    Inventors: Zhiwei WANG, Yunhang GUO, Desheng YU
  • BTK inhibitors with improved dual selectivity
    Patent number: 11377449
    Abstract: Disclosed herein is a tri-substituted phenyl Btk inhibitors with improved dual selectivity, a method and a composition for inhibiting Btk and treating disease associated with undesirable Btk activity (Btk-related diseases).
    Type: Grant
    Filed: August 12, 2018
    Date of Patent: July 5, 2022
    Assignee: BEIGENE, LTD.
    Inventors: Zhiwei Wang, Yunhang Guo, Desheng Yu
  • CRYSTALLINE FORMS OF (S)-7-(1-(BUT-2-YNOYL)PIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-a]PYRIMIDINE-3-CARBOXAMIDE, PREPARATION, AND USES THEREOF
    Publication number: 20210332049
    Abstract: The present invention relates to a crystalline form of (S)-7-(1-(but-2-ynoyl) piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo [1,5-a] pyrimidine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.
    Type: Application
    Filed: January 25, 2018
    Publication date: October 28, 2021
    Inventors: Yunhang GUO, Desheng YU, Zhiwei WANG
  • BTK INHIBITORS WITH IMPROVED DUAL SELECTIVITY
    Publication number: 20200181150
    Abstract: Disclosed herein is a tri-substituted phenyl Btk inhibitors with improved dual selectivity, a method and a composition for inhibiting Btk and treating disease associated with undesirable Btk activity (Btk-related diseases).
    Type: Application
    Filed: August 12, 2018
    Publication date: June 11, 2020
    Inventors: Zhiwei WANG, Yunhang GUO, Desheng YU