Patents by Inventor Desmond Mascarenhas

Desmond Mascarenhas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240034761
    Abstract: Methods and compositions involving synthetic immodulin peptides and helper molecules. The peptides exhibit new and surprising biological activities, such as co-stimulation of macrophage and myogenic cell differentiation markers. Methods are provided N by which peptide is contacted with one or more myeloid precursor cell populations, thereby increasing the abundance of CD169+, CCL22+, Clec4A, Clec9a+, and Clec 12a+ monocyte lineages which play important roles in cross presentation, post-apoptotic clearance, autoimmunity, and programmatic tissue regeneration, notably in contexts of tissue stress, insult and degeneration. The disclosed methods and compositions enable concurrent regeneration of diverse cellular elements in tissue where collaborating myeloid and non-myeloid lineages are located together in a living tissue following the contacting steps.
    Type: Application
    Filed: March 2, 2022
    Publication date: February 1, 2024
    Inventor: Desmond Mascarenhas
  • Patent number: 8536135
    Abstract: The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human disease. The methods described herein comprise contacting a provocative agent to live cells and measuring and analyzing adaptive readouts. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: September 17, 2013
    Assignee: Ontherix, Inc.
    Inventor: Desmond Mascarenhas
  • Publication number: 20120252722
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 4, 2012
    Inventor: Desmond MASCARENHAS
  • Publication number: 20120041801
    Abstract: A computer-implemented system for creating a classification significance pattern for end users, and enabling end users to use their classification significance pattern to conduct custom searches for target information, such as information about products, services, and jobs, as well as enabling third parties, such as vendors and potential employers, to target their advertisements to groups of users meeting a certain classification. A classification significance pattern is created by having a user take a psychological test, for example, that includes a personality test, a design taste test, a recreation/travel test, a life satisfaction test, an interactive game module, or a career/job test, and having the system automatically score such test and classifying the user based on a defined abstract classification.
    Type: Application
    Filed: August 17, 2011
    Publication date: February 16, 2012
    Applicant: PROTIGEN, INC.
    Inventor: Desmond MASCARENHAS
  • Publication number: 20110212079
    Abstract: The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human disease. The methods described herein comprise contacting a provocative agent to live cells and measuring and analyzing adaptive readouts. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: February 25, 2011
    Publication date: September 1, 2011
    Inventor: Desmond MASCARENHAS
  • Patent number: 8010400
    Abstract: A computer-implemented system for creating a classification significance pattern for end users, and enabling end users to use their classification significance pattern to conduct custom searches for target information, such as information about products, services, and jobs, as well as enabling third parties, such as vendors and potential employers, to target their advertisements to groups of users meeting a certain classification. A classification significance pattern is created by having a user take a psychological test, for example, that includes a personality test, a design taste test, a recreation/travel test, a life satisfaction test, an interactive game module, or a career/job test, and having the system automatically score such test and classifying the user based on a defined abstract classification.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: August 30, 2011
    Assignee: Protigen, Inc.
    Inventor: Desmond Mascarenhas
  • Publication number: 20110202281
    Abstract: The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human disease. The methods described herein comprise contacting a provocative agent to live cells and measuring and analyzing adaptive readouts. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: March 19, 2009
    Publication date: August 18, 2011
    Applicant: ONTHERIX, INC.
    Inventor: Desmond Mascarenhas
  • Publication number: 20100152113
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: November 20, 2009
    Publication date: June 17, 2010
    Inventor: Desmond Mascarenhas
  • Patent number: 7662624
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: February 16, 2010
    Assignee: Ontherix, Inc.
    Inventor: Desmond Mascarenhas
  • Patent number: 7618816
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: November 17, 2009
    Assignee: Ontherix, Inc.
    Inventor: Desmond Mascarenhas
  • Patent number: 7611893
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: November 3, 2009
    Assignee: Ontherix, Inc.
    Inventor: Desmond Mascarenhas
  • Publication number: 20090053203
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: March 19, 2008
    Publication date: February 26, 2009
    Inventor: Desmond Mascarenhas
  • Publication number: 20080124346
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: March 19, 2007
    Publication date: May 29, 2008
    Inventor: Desmond Mascarenhas
  • Patent number: 7371813
    Abstract: New methods for the treatment of human disease are provided. IGFBP-3 is administered together with a co-administered agent to subjects having disease, thereby alleviating the symptoms of the disease, under conditions where administration of IGFBP-3 alone at the maximum practicable dose has no measurable beneficial effect on the disease condition.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: May 13, 2008
    Assignee: Bioexpertise LLC
    Inventor: Desmond Mascarenhas
  • Publication number: 20080039393
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: June 1, 2007
    Publication date: February 14, 2008
    Inventor: Desmond Mascarenhas
  • Patent number: 7288516
    Abstract: New methods for the treatment of cancer are provided. Null IGF (IGF variants with reduced receptor binding) is administered to subjects having cancer, thereby alleviating the symptoms of the cancer.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: October 30, 2007
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventor: Desmond Mascarenhas
  • Publication number: 20070141069
    Abstract: New methods for the treatment of human disease are provided. IGFBP-3 is administered together with a co-administered agent to subjects having disease, thereby alleviating the symptoms of the disease, under conditions where administration of IGFBP-3 alone at the maximum practicable dose has no measurable beneficial effect on the disease condition.
    Type: Application
    Filed: January 29, 2007
    Publication date: June 21, 2007
    Inventor: Desmond Mascarenhas
  • Publication number: 20070134257
    Abstract: The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: November 8, 2006
    Publication date: June 14, 2007
    Inventor: Desmond Mascarenhas
  • Publication number: 20070128113
    Abstract: The present invention is related to methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
    Type: Application
    Filed: April 14, 2006
    Publication date: June 7, 2007
    Applicant: BIOEXPERTISE LLC
    Inventors: Desmond Mascarenhas, Baljit Singh
  • Patent number: 7213032
    Abstract: This invention relates generally to a computer-implemented method and system for having anonymous profiling of, and marketing to, anonymous users in a data network, particularly in the Internet. It enables an individual to surf the Internet anonymously as well as enabling third parties to use profiling information to target such anonymous users. The real identity of the individual is never known within the anonymous trust system.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: May 1, 2007
    Assignee: Protigen, Inc.
    Inventor: Desmond Mascarenhas