Patents by Inventor Detcho A. Stoyanovsky

Detcho A. Stoyanovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mitochondria-targeted inhibitors of cytochrome c peroxidase for protection from apoptosis
    Patent number: 9365597
    Abstract: The present application is directed to novel imidazole-substituted fatty acids that have been functionalized with an alkyl triphenylphosphonium group, compositions comprising these compounds and their use as inhibitors of cytochrome c peroxidase, in particular for the treatment and prevention of apoptosis.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: June 14, 2016
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Brock University
    Inventors: Jeffrey Atkinson, Jeffrey Stuart, Valarian E. Kagan, Detcho A. Stoyanovsky, Michael W. Epperly, Joel S. Greenberger, Hülya Bayîr
  • Mitochondria-Targeted Inhibitors of Cytochrome C Peroxidase for Protection from Apoptosis
    Publication number: 20130203829
    Abstract: The present application is directed to novel imidazole-substituted fatty acids that have been functionalized with an alkyl triphenylphosphonium group, compositions comprising these compounds and their use as inhibitors of cytochrome c peroxidase, in particular for the treatment and prevention of apoptosis.
    Type: Application
    Filed: November 13, 2012
    Publication date: August 8, 2013
    Inventors: Jeffrey Atkinson, Jeffrey Stuart, Valarian E. Kagan, Detcho A. Stoyanovsky, Michael W. Epperly, Joel S. Greenberger
  • Method of treating cancerous disease
    Publication number: 20030068386
    Abstract: This invention discloses a method of treating a patient having a cancerous disease comprising administering to the patient an effective amount of a composition capable of generating a hydroxyl radical, wherein the extracellular pH of the cancer cells is less than 7.0. Preferably, the method includes employing N-substituted hydroxyl amines as the composition capable of generating the hydroxyl radical.
    Type: Application
    Filed: September 5, 2001
    Publication date: April 10, 2003
    Inventor: Detcho A. Stoyanovsky