Abstract: The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

Abstract: The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

Abstract: The invention is directed to a spinal fusion cage for implantation between two adjacent vertebrae, wherein the total cage has, under a load, a maximum compression that is higher than 0.05% of the original height of the spinal fusion cage and the maximum compression does not change the structural integrity of the cage.

Abstract: The invention is directed to an orthopedic implant comprising different distinct sections, wherein each section comprises a different polymeric material and the polymeric materials are at the contact surfaces of the sections attached to each other by chemical bonds and/or physical interaction and to a method for the production of an orthopedic implant wherein multi-component molding is used.

Abstract: The invention is directed to a spinal fusion cage for implantation between two adjacent vertebrae, wherein the total cage has, under a load, a maximum compression that is higher than 0.05% of the original height of the spinal fusion cage and the maximum compression does not change the structural integrity of the cage.