Patents by Inventor Detlef STOECKIGT

Detlef STOECKIGT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160120854
    Abstract: The present invention relates to pharmaceutical compositions of substituted triazolopyridine compounds of general formula (I) as described and defined herein, to methods of preparing said compositions, and to the use of the compositions for the treatment or prophylaxis of a disease.
    Type: Application
    Filed: June 5, 2014
    Publication date: May 5, 2016
    Inventors: Volker SCHULZE, Michael BRÜNING, Detlef STÖCKIGT
  • Publication number: 20150368260
    Abstract: The present invention relates to isothiazoles of general formula (I) which inhibit the mitotic checkpoint: in which A, R1 and R2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: January 28, 2014
    Publication date: December 24, 2015
    Inventors: Lars BÄRFACKER, Stefan PRECHTL, Gerhard SIEMEISTER, Antje Margret WENGNER, Jens ACKERSTAFF, Katrin NOWAK-REPPEL, Benjamin BADER, Philip LIENAU, Detlef STÖCKIGT, Tobias HEINRICH
  • Publication number: 20150344444
    Abstract: The present invention relates to BET protein-inhibitory, especially BRD4-inhibitory, dihydroquinoxalinones of the general formula (I) in which A, X, R1, R2, R3, R4, R5, R6, R7 and n are each as defined in the description, to intermediates for preparation of the inventive compounds, to pharmaceutical compositions comprising the inventive compounds, and to the prophylactic and therapeutic use thereof in the case of hyperproliferative disorders, especially in the case of neoplastic disorders. This invention further relates to the use of BET protein inhibitors in viral infections, in neurodegenerative disorders, in inflammation disorders, in atherosclerotic disorders and in male fertility control.
    Type: Application
    Filed: December 17, 2013
    Publication date: December 3, 2015
    Inventors: Norbert SCHMEES, Bernard HAENDLER, Detlef STÖCKIGT, Daniel GALLENKAMP
  • Publication number: 20150210683
    Abstract: The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: December 10, 2012
    Publication date: July 30, 2015
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Volker Schulze, Dirk Kosemund, Antje Margret Wengner, Gerhard Siemeister, Detlef Stöckigt, Michael Brüning
  • Publication number: 20140120087
    Abstract: The present invention relates to triazolopyridine compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: April 16, 2012
    Publication date: May 1, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Volker Schulze, Dirk Kosemund, Antje Margret Wengner, Gerhard Siemeister, Detlef Stöckigt, Philip Lienau, Hartmut Schirok, Hans Briem
  • Publication number: 20130156756
    Abstract: The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease of uncontrolled cell growth, proliferation and/or survival as well as to the use of intermediate compounds for the preparation of said compounds.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 20, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Volker Schulze, Dirk Kosemund, Hartmut Schirok, Benjamin Bader, Philip Lienau, Antje Margret Wengner, Hans Briem, Simon Holton, Gerhard Siemeister, Stefan Prechtl, Marcus Koppitz, Detlef Stöckigt, Olaf Prien
  • Patent number: 6824982
    Abstract: The present invention relates to a method for determining the enantioselectivity of kinetic resolution processes and of asymmetrically proceeding reactions of prochiral compounds bearing enantiotopic groups by using isotope-labeled substrates so that the reaction products can be quantitatively determined with an isotope-specific detection system, e.g., an ESI mass spectrometer. In connection with automated sample charging, the method can be employed for high throughput screening. The relevant enantioselective conversions can be induced by chiral homogeneous or heterogeneous catalysts, biocatalysts or stoichiometric amounts of optically active agents.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: November 30, 2004
    Assignee: Studiengesellschaft Kohle mbH
    Inventors: Manfred T. Reetz, Michael Heinrich Becker, Detlef Stöckigt, Heinz-Werner Klein