Abstract: The invention relates to a microkeratome (1) for use in a LASEK procedure as well as to a knife (3) with a blade (6) for a microkeratome, said blade (6) having a defined bluntness. In order to avoid loosening of the epithelium with an alcoholic solution in the LASEK procedure, the epithelium is sliced away to leave a remaining hinge, this being achieved by means of the microkeratome (1) into which the knife (3) is inserted. The blade (6) of the knife (3) has a defined bluntness to prevent Bowman's membrane from being injured by the cut in the epithelium. It comprises a cutting-edge angle (?) ranging from 28 degrees to 35 degrees, a clearance angle (?) ranging from 0 degrees to 4 degrees, and a blade radius (R) ranging from 150 nm to 800 nm.

Abstract: The present invention provides a microkeratome for creating lamellar sections from a biological tissue containing a blade-post assembly which improves precision and predictability by preventing undesired blade wobbling. Methods and devices are disclosed to inhibit blade wobbling, preferably frictional fittings are employed to secure the blade (or blade assembly) within the microkeratome. By biasing the blade into a secure position, wobbling during usage is substantially lessened if not eliminated. A modified blade assembly is disclosed having a post that is mated to a surgical blade. In one embodiment of the invention, the post can have one or more protrusions that engage at least one side of a recess in the microkeratome thereby creating a frictional fit sufficient to prevent movement of the blade while cutting. In another embodiment of the invention, the recess can include certain biasing elements that engage the post to prevent blade wobbling.