Patents by Inventor Dev Karan

Dev Karan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of manzamines as antiproliferative agent
    Patent number: 12023330
    Abstract: Described herein are methods and systems for using an alkaloid, such as manzamine A, for anti-proliferative effects at relatively low and non-cytotoxic concentrations (up to 4 ?M) wherein manzamine A blocks cell cycle progression in cervical cancer cell lines and regulates cell cycle-related genes, including restoration of p21 and p53 expression inducing apoptosis.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: July 2, 2024
    Inventors: Dev Karan, Mark T. Hamann
  • CCL24 as a diagnostic and therapeutic target for breast cancer
    Patent number: 11988672
    Abstract: Using expression of CC chemokine ligand (CCL24) to serve as an identification of a potential deriver of metastatic cancers and methods of detecting the presence of CCL24 to serve as a breast cancer diagnosis tool.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: May 21, 2024
    Assignee: University of South Carolina
    Inventors: Dev Karan, Seema Dubey
  • USE OF MANZAMINES AS ANTIPROLIFERATIVE AGENT
    Publication number: 20210244725
    Abstract: Described herein are methods and systems for using an alkaloid, such as manzamine A, for anti-proliferative effects at relatively low and non-cytotoxic concentrations (up to 4 ?M) wherein manzamine A blocks cell cycle progression in cervical cancer cell lines and regulates cell cycle-related genes, including restoration of p21 and p53 expression inducing apoptosis.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 12, 2021
    Applicant: University of South Carolina
    Inventors: Dev Karan, Mark T. Hamann
  • CCL24 as a Diagnostic and Therapeutic Target for Breast Cancer
    Publication number: 20210208161
    Abstract: Using expression of CC chemokine ligand (CCL24) to serve as an identification of a potential deriver of metastatic cancers and methods of detecting the presence of CCL24 to serve as a breast cancer diagnosis tool.
    Type: Application
    Filed: November 24, 2020
    Publication date: July 8, 2021
    Applicant: University of South Carolina
    Inventors: Dev Karan, Seema Dubey