Abstract: Electrical characteristics of an electrical signal generated by an affinity-based senor are detected, where the affinity-based sensor is configured to bind to a particular biomarker within a body fluid sample and generate the electrical signal based on binding to the particular biomarker. One or more biometric characteristics of a subject are further detected from one or more other sensors. A data set comprising data describing each of the electrical characteristics and each of the one or more biometric characteristics is provided as an input to a machine learning model, which generates an output based on the input that identifies an amount of the particular biomarker present in the body fluid sample based on the input.

Abstract: Systems, methods, and devices include a high-density analog multiplexer topology. Such topologies can be used, for example, in sensor device applications. An analog multiplexer circuit can include circuitry to receive N input signals; and circuitry to generate N selection signals for selecting one of said N data signals to be output from said analog multiplexer circuit. The analog multiplexer comprises one or more analog impedances.