Abstract: This disclosure provides cyanine dye compounds having linked hydrogen bond-forming groups that can be used for detecting nucleic acids, particularly for fluorescent staining of DNA, in a biological sample. We found that the simultaneous incorporation of at least two hydrogen bond-forming groups (HBGs) into such a nucleic acid stain can provide for crosslinking interactions between the stain and the target nucleic acid, and lead to a significant increase in the detection sensitivity without substantially increasing undesirable cytotoxicity or mutagenicity properties of the dye compounds. The cyanine dye compounds can have a cyanine structure that connects two particular fused heterocycle ring systems, where at least two HBGs are connected to the core structure through linkers. Also provided are nucleic acid complexes including the cyanine dye compounds, and methods of using the compounds to detect nucleic acids in a biological sample.

Abstract: A levodopa derivative including a compound or pharmaceutically acceptable salt, hydrate, and/or solvate thereof, wherein the compound includes substituents which, in aggregate, contain at least 6 carbon atoms which are only bonded to either other carbon atoms or to hydrogen atoms. The levodopa derivative may be formulated as a composition including one or more pharmaceutically acceptable carriers or excipients. The levodopa derivative may be part of a pharmaceutical composition including micro or nano particles in which the levodopa derivative is encapsulated in the pharmaceutically acceptable polymer. The levodopa derivative can be used to treat Parkinson's disease by administering to a mammal an amount sufficient to treat Parkinson's disease.

Abstract: An example cooling system for a wireless networking device is presented. The cooling system includes a Peltier cooler disposed in thermal contact with a radio-frequency (RF) filter coupled to a transceiver disposed in the wireless networking device. Further, the cooling system includes a thermal management controller coupled to the Peltier cooler and the transceiver. The thermal management controller is configured to receive a signal indicating whether the transceiver is performing a data communication. In response to determining that the transceiver is performing the data communication, the thermal management controller operates the Peltier cooler to actively cool the RF filter. However, in response to determining that the transceiver is not performing the data communication while the wireless networking device is powered on, the thermal management controller operates the Peltier cooler to stop actively cooling the RF filter.

Abstract: This disclosure provides cyanine dye compounds having linked hydrogen bond-forming groups that can be used for detecting nucleic acids, particularly for fluorescent staining of DNA, in a biological sample. We found that the simultaneous incorporation of at least two hydrogen bond-forming groups (HBGs) into such a nucleic acid stain can provide for crosslinking interactions between the stain and the target nucleic acid, and lead to a significant increase in the detection sensitivity without substantially increasing undesirable cytotoxicity or mutagenicity properties of the dye compounds. The cyanine dye compounds can have a cyanine structure that connects two particular fused heterocycle ring systems, where at least two HBGs are connected to the core structure through linkers. Also provided are nucleic acid complexes including the cyanine dye compounds, and methods of using the compounds to detect nucleic acids in a biological sample.

Abstract: A system or Access Point having a split band architecture. A first radio communicates with a 6G front end module (FEM) that is connected to a first filter switch bank (FSB) configured to enable a 6G high bandpass filter, a 6G wide bandpass filter, or a 6G narrow bandpass filter. A second radio communicates with a 5G FEM that is connected to a second FSB configured to enable a 6G low bandpass filter, a first 5G low bandpass filter, a 5G wide bandpass filter, or a 5G narrow bandpass filter. A third radio communicates with a 2-5G dual band FEM that is connected to a third FSB configured to enable a 6G full bandpass filter, a 5G high bandpass filter, or a second 5G low bandpass filter. The 2-5G dual FEM may also be connected to a fourth FSB configured to enable a 2G application.

Abstract: This disclosure provides cyanine dye compounds having linked hydrogen bond-forming groups that can be used for detecting nucleic acids, particularly for fluorescent staining of DNA, in a biological sample. We found that the simultaneous incorporation of at least two hydrogen bond-forming groups (HBGs) into such a nucleic acid stain can provide for crosslinking interactions between the stain and the target nucleic acid, and lead to a significant increase in the detection sensitivity without substantially increasing undesirable cytotoxicity or mutagenicity properties of the dye compounds. The cyanine dye compounds can have a cyanine structure that connects two particular fused heterocycle ring systems, where at least two HBGs are connected to the core structure through linkers. Also provided are nucleic acid complexes including the cyanine dye compounds, and methods of using the compounds to detect nucleic acids in a biological sample.

Abstract: Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations are provided.

Abstract: Systems and methods for providing low latency connection by a network device is described herein. Upon receiving a request for a low latency connection from a client device, a lower frequency filter in a primary 6 GHz radio, a secondary 6 GHz radio and an upper frequency filter in the secondary 6 GHz radio may be enabled. A transition band between the lower frequency filter and the upper frequency filter may be enabled such that there is no interference between a primary frequency channel allowed by the lower frequency filter and a secondary frequency channel allowed by the upper frequency filter. An operating frequency channel of an existing communication session with the client device may be determined. Based on the operating frequency channel, the primary frequency channel and the secondary frequency channel may be determined to provide a first communication connection and a second communication connection to the client device.

Abstract: Systems and techniques are described that are directed to filter frequency response shift compensation, including compensating for shifting in the rejection band of the filter. Compensation for the shifting in the rejection band can include applying a pre-distortion to attenuate edge resource units (RUs), and applying PHY Protocol Data Unit (PPDU) scheduling schemes. For example, a PPDU scheduling scheme reduce bandwidth in the channel, thereby dropping the out of band RUs. Front ends provide feedback to a respective radio, which allows that radio to apply the appropriate pre-distortion. The front ends can include one or more filters enabling frequency domain coexistence between collocated radios operating in the differing Wi-Fi bands, and a coupler that provides the feedback indicating the frequency response shift to a radio. The radio can then apply a digital pre-distortion to compensate for the shifting in the rejection band.

Abstract: A levodopa derivative including a compound or pharmaceutically acceptable salt, hydrate, and/or solvate thereof, wherein the compound includes substituents which, in aggregate, contain at least 6 carbon atoms which are only bonded to either other carbon atoms or to hydrogen atoms. The levodopa derivative may be formulated as a composition including one or more pharmaceutically acceptable carriers or excipients. The levodopa derivative may be part of a pharmaceutical composition including micro or nano particles in which the levodopa derivative is encapsulated in the pharmaceutically acceptable polymer. The levodopa derivative can be used to treat Parkinson's disease by administering to a mammal an amount sufficient to treat Parkinson's disease.

Abstract: Compounds of formula I and II: or a pharmaceutically acceptable salt thereof, and their compositions including polymer encapsulated micro/nano particle compositions are provided, wherein: R1 is —CH2—, a C2-6 straight or branched chain alkylene, alkenylene or alkynylene group or a short chain polyethylene glycol group having 2-6 monomers, or a combination thereof; R2 is hydrogen or —(C?O)R3 wherein R3 is a C2-6 straight or branched chain alkylene, alkenylene or alkynylene group or a short chain polyethylene glycol group having 2-6 monomers, or a combination thereof; and R4 is a pharmaceutically acceptable polymeric moiety comprising a pharmaceutically acceptable polymer chain such that R1 is linked to the polymer chain through an ester, carbonate or carbamate bond including the oxygen atom linking R1 and R4. The compositions are useful for treatment of multiple myeloma, mantle cell lymphoma, and transfusion-dependent anemia due to myelodysplastic syndromes.

Abstract: Systems and methods are provided by which all APs in a particular deployment can be used to assist in the out-of-band discovery of 6 GHz radios by client devices. That is, a series of iterative operations can be performed to: (I) determine the state of 6 GHz radios in a zone/deployment area; (II) identify what radios can be considered near-neighbors to non-6 GHz radios for purposes of advertising one or more of the 6 GHz radios; (Ill) rank neighboring 6 GHz radios for a given non-6 GHz radio based on certain radio metrics; and (IV) ultimately determine those 6 GHz radios that can be advertised by the given non-6 GHz radio.

Abstract: Dynamic configuration of multiple radios of an access point is described. An example of an access point includes a processor; a memory; hardware filters; and a first set of radio chains and antennas, the access point including a first radio mode for operation as a single radio on a first channel to service a first BSS and a second radio mode for operation as a first radio on the first channel and a second radio on a second channel to perform an additional service, wherein the access point is to provide dynamic configuration of the radios including, upon determining that operation of the first channel to service the first BSS is not compatible with a particular hardware filter of the first radio, migrating the first BSS from the first radio to the second radio to service on the second channel, and providing the additional service on the first channel.

Abstract: Systems and techniques are described that are directed to filter frequency response shift compensation, including compensating for shifting in the rejection band of the filter. Compensation for the shifting in the rejection band can include applying a pre-distortion to attenuate edge resource units (RUs), and applying PHY Protocol Data Unit (PPDU) scheduling schemes. For example, a PPDU scheduling scheme reduce bandwidth in the channel, thereby dropping the out of band RUs. Front ends provide feedback to a respective radio, which allows that radio to apply the appropriate pre-distortion. The front ends can include one or more filters enabling frequency domain coexistence between collocated radios operating in the differing Wi-Fi bands, and a coupler that provides the feedback indicating the frequency response shift to a radio. The radio can then apply a digital pre-distortion to compensate for the shifting in the rejection band.

Abstract: Systems and techniques are described that are directed to filter frequency response shift compensation, including compensating for shifting in the rejection band of the filter. Compensation for the shifting in the rejection band can include applying a pre-distortion to attenuate edge resource units (RUs), and applying PHY Protocol Data Unit (PPDU) scheduling schemes. For example, a PPDU scheduling scheme reduce bandwidth in the channel, thereby dropping the out of band RUs. Front ends provide feedback to a respective radio, which allows that radio to apply the appropriate pre-distortion. The front ends can include one or more filters enabling frequency domain coexistence between collocated radios operating in the differing Wi-Fi bands, and a coupler that provides the feedback indicating the frequency response shift to a radio. The radio can then apply a digital pre-distortion to compensate for the shifting in the rejection band.

Abstract: Systems and methods are provided by which all APs in a particular deployment can be used to assist in the out-of-band discovery of 6 GHz radios by client devices. That is, a series of iterative operations can be performed to: (I) determine the state of 6 GHz radios in a zone/deployment area; (II) identify what radios can be considered near-neighbors to non-6 GHz radios for purposes of advertising one or more of the 6 GHz radios; (Ill) rank neighboring 6 GHz radios for a given non-6 GHz radio based on certain radio metrics; and (IV) ultimately determine those 6 GHz radios that can be advertised by the given non-6 GHz radio.

Abstract: Example implementations relate to an electronic plug having a locking assembly for securing within an electronic port having a receptacle. The locking assembly includes a cantilever beam, a deformable arm, and an axle rotatably coupled to a connector of the electronic plug. The cantilever beam extends from the axle, where a free end of the cantilever beam includes a locking tab aligned to a recess of the connector. The deformable arm extends from the axle, where an open end of the deformable arm is rested on the connector. In a biased state of the deformable arm, the locking tab is positioned below the recess to allow movement of the connector in and out of the receptacle. In a relaxed state of the deformable arm, the locking tab protrudes above the recess to allow movement of the connector into the receptacle and prevent movement of the connector out of the receptacle.

Abstract: Systems and methods are provided for optimizing the scheduling of Orthogonal Frequency-Division Multiple Access (OFDMA) transmissions in the downlink (DL) direction. A two-stage mechanism can be implemented when effectuating DL OFDMA transmission involving multiple modulation and coding schemes (MCS) in a single transmit burst. A first stage of the two-stage mechanism may use radio frequency (RF) boosting/de-boosting of Resource Units (RUs) such that the average input power to an AP power amplifier (PA) may remain under a saturated PA output power to ensure PA linearity. If RF boosting/de-boosting is not supported, an alternative mechanism for OFDMA grouping (to rigid grouping) can be employed to skip higher MCS.

Abstract: Systems and techniques are described that are directed to filter frequency response shift compensation, including compensating for shifting in the rejection band of the filter. Compensation for the shifting in the rejection band can include applying a pre-distortion to attenuate edge resource units (RUs), and applying PHY Protocol Data Unit (PPDU) scheduling schemes. For example, a PPDU scheduling scheme reduce bandwidth in the channel, thereby dropping the out of band RUs. Front ends provide feedback to a respective radio, which allows that radio to apply the appropriate pre-distortion. The front ends can include one or more filters enabling frequency domain coexistence between collocated radios operating in the differing Wi-Fi bands, and a coupler that provides the feedback indicating the frequency response shift to a radio. The radio can then apply a digital pre-distortion to compensate for the shifting in the rejection band.

Abstract: One embodiment can provide a method and a system for performing multiple radio frequency allocation. During operation, the system including a controller can receive, a Wi-Fi channel allocation and a filter bank configuration associated with a Wi-Fi radio transceiver. The system can determine one or more Internet of things (IoT) radio transceivers operating with the Wi-Fi radio transceiver. For a respective IoT radio transceiver, the system can perform the following operations: determining a set of scores based on a set of constraints associated with an application type for the IoT radio transceiver; and computing a weighted average score based on the set of scores; and determining a channel allocation for the IoT radio transceiver based on the weighted average score and the Wi-Fi channel allocation.