Patents by Inventor Devin M. Stranford

Devin M. Stranford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXTRACELLULAR VESICLES COMPRISING TARGETING AFFINITY DOMAIN-BASED MEMBRANE PROTEINS
    Publication number: 20210030850
    Abstract: Disclosed are extracellular vesicles comprising an engineered targeting protein for targeting the extracellular vesicles to target cells. The targeting protein is a fusion protein that includes (i) an affinity agent, such as a single-chain variable fragment of an antibody (scFv), which is expressed on the surface of the extracellular vesicles and (ii) a transmembrane domain, and may include additional domains. Exemplary extracellular vesicles may include but are not limited to exosomes or microvesicles.
    Type: Application
    Filed: April 10, 2019
    Publication date: February 4, 2021
    Applicant: Northwestern University
    Inventors: Joshua N. LEONARD, Devin M. STRANFORD
  • DELIVERABLE EXTRACELLULAR VESICLES INCORPORATING CELL MEMBRANE TRANSPORT PROTEINS
    Publication number: 20180325998
    Abstract: Disclosed are extracellular vesicles (EVs), such as exosomes, comprising a heterologous cell membrane transporter protein, such as the sodium iodide symporter (NIS). Also disclosed are methods of using the disclosed EVs for delivering agents to recipient cells and methods for measuring efficacy of delivery by the EVs to the recipient cells. Also disclosed are method of making the disclosed EVs and cell lines for producing the EVs.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 15, 2018
    Applicant: Northwestern University
    Inventors: Joshua N. Leonard, Devin M. Stranford, Michael J. Passineau