Patents by Inventor Devin McAllister
Devin McAllister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230381478Abstract: A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.Type: ApplicationFiled: August 14, 2023Publication date: November 30, 2023Inventors: Devin McAllister, Mark R. Prausnitz, Sebastien Henry, Xin Dong Guo
-
Patent number: 11724079Abstract: A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.Type: GrantFiled: October 1, 2020Date of Patent: August 15, 2023Assignee: Georgia Tech Research CorporationInventors: Devin McAllister, Mark R. Prausnitz, Sebastien Henry, Xin Dong Guo
-
Publication number: 20230226334Abstract: Microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.Type: ApplicationFiled: February 27, 2023Publication date: July 20, 2023Inventors: Devin McAllister, Mark R. Prausnitz, Sebastien Henry, James J. Norman
-
Patent number: 11590330Abstract: Microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.Type: GrantFiled: April 15, 2019Date of Patent: February 28, 2023Assignee: Georgia Tech Research CorporationInventors: Devin McAllister, Mark R. Prausnitz, Sebastien Henry, James J. Norman
-
Publication number: 20210016071Abstract: A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Inventors: Devin MCALLISTER, Mark R. PRAUSNITZ, Sebastien HENRY, Xin Dong GUO
-
Patent number: 10828478Abstract: A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.Type: GrantFiled: April 24, 2015Date of Patent: November 10, 2020Assignee: Georgia Tech Research CorporationInventors: Devin McAllister, Mark Prausnitz, Sebastien Henry, Xin Dong Guo
-
Publication number: 20190240469Abstract: Microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.Type: ApplicationFiled: April 15, 2019Publication date: August 8, 2019Inventors: Devin McAllister, Mark R. Prausnitz, Sebastien Henry, James J. Norman
-
Patent number: 10265511Abstract: Embodiments of the present application provide microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.Type: GrantFiled: September 30, 2014Date of Patent: April 23, 2019Assignee: Georgia Tech Research CorporationInventors: Devin McAllister, Mark Prausnitz, Sabastien Henry, James J. Norman
-
Publication number: 20170050010Abstract: A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.Type: ApplicationFiled: April 24, 2015Publication date: February 23, 2017Inventors: Devin MCALLISTER, Mark PRAUSNITZ, Sebastien HENRY, Xin Dong GUO
-
Publication number: 20160213908Abstract: Embodiments of the present application provide microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents.Type: ApplicationFiled: September 30, 2014Publication date: July 28, 2016Inventors: Devin McAllister, Mark Prausnitz, Sabastien Henry, James J. Norman
-
Patent number: 7303726Abstract: A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the biologic fluid sample after a lancet and lancing device are used in combination to pierce the skin. The system preferably includes a device comprising two body portions that slide relative to each other to both cock and fire a test strip at a target site. Meter reading and test strip disposal may be accomplished by removing the device from the target site. The device preferably employs a magazine loaded with test strips, with one strip being taken from the magazine each time the device is actuated. It preferably also includes a magazine in a cap to store spent test strips for disposal. The device may be turned on an off simply by removal and return of the cap.Type: GrantFiled: May 9, 2002Date of Patent: December 4, 2007Assignee: Lifescan, Inc.Inventors: Devin McAllister, Lorin Olson, Borzu Sohrab
-
Publication number: 20070078414Abstract: The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.Type: ApplicationFiled: August 5, 2005Publication date: April 5, 2007Inventors: Devin McAllister, Ciro DiMeglio
-
Patent number: 7144495Abstract: Methods and devices for electrochemically detecting a change in the viscosity of a fluid are provided. In the subject methods, a fluid sample (e.g., a whole blood sample) is introduced into an electrochemical test strip's electrochemical cell using a micro-needle integrated into one of oppositely spaced apart working and reference electrodes. An electric potential is applied to the electrochemical cell to first achieve a steady state cell current. A decrease in the steady state cell current is then detected and related to a change in viscosity of the sample. In many embodiments, the sample is blood and the change in viscosity is related to the onset of coagulation in the blood sample, and often the PT of the blood sample. An electrochemical test strip includes an electrochemical cell and an integrated micro-needle. The electrochemical cell includes oppositely spaced apart working and reference electrodes and a reagent mixture (e.g., a redox couple and a coagulation catalyzing agent).Type: GrantFiled: August 23, 2002Date of Patent: December 5, 2006Assignee: Lifescan, Inc.Inventors: Maria Teodorczyk, Ernest J. Kiser, Lorin P. Olson, Devin McAllister, Vadim V. Yuzhakov, Koon-wah Leong
-
Publication number: 20050187525Abstract: A bodily fluid extraction device includes a penetration member configured for penetrating a target site and subsequently residing within the target site and extracting a bodily fluid sample. The penetration member includes a proximal end adapted for fluid communication with an analyte analysis system, a distal end, and a channel extending from the distal to the proximal end. The distal end includes a sharp portion for penetrating a target site, and a flexible feature adapted for promoting bodily fluid flow into the channel by protruding into the target site after the penetration member has penetrated the target site. A method for extracting bodily fluid includes providing a bodily fluid extraction device as described immediately above.Type: ApplicationFiled: February 19, 2004Publication date: August 25, 2005Inventors: Michael Hilgers, Devin McAllister, Adolfo Menendez
-
Publication number: 20050137531Abstract: Microneedle devices and methods of use thereof are provided for the enhanced transport of molecules, including drugs and biological molecules, across tissue by improving the interaction of microneedles and a deformable, elastic biological barrier, such as human skin. The devices and methods act to (1) limit the elasticity, (2) adapt to the elasticity, (3) utilize alternate ways of creating the holes for the microneedles to penetrate the biological barrier, other than the simply direct pressure of the microneedle substrate to the barrier surface, or (4) any combination of these methods. In preferred embodiments for limiting the elasticity of skin, the microneedle device includes features suitable for stretching, pulling, or pinching the skin to present a more rigid, less deformable, surface in the area to which the microneedles are applied (i.e. penetrate).Type: ApplicationFiled: May 28, 2004Publication date: June 23, 2005Inventors: Mark Prausnitz, Mark Allen, Sebastian Henry, Devin McAllister, Donald Ackley, Thomas Jackson
-
Publication number: 20030223906Abstract: A test strip container is disclosed. It is adapted to individually receive a plurality of test strips in a sealed fashion. A foil seal and/or mechanical seal may be provided that allows access/exposure to one test strip at a time. The container may also include a waste receptacle that can be closed-off for safe storage of spent test strips. The container may be used separately from a meter/lancing device which accepts and uses test strips or the container may itself be at least partially loaded into a meter for a more direct interface. The subject devices as well as methodology associated with their use is described. Kits including at least one subject device are also provided.Type: ApplicationFiled: June 3, 2002Publication date: December 4, 2003Inventors: Devin McAllister, Koon-Wah Leong
-
Publication number: 20030212345Abstract: A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the biologic fluid sample after a lancet and lancing device are used in combination to pierce the skin. The system preferably includes a device comprising two body portions that slide relative to each other to both cock and fire a test strip at a target site. Meter reading and test strip disposal may be accomplished by removing the device from the target site. The device preferably employs a magazine loaded with test strips, with one strip being taken from the magazine each time the device is actuated. It preferably also includes a magazine in a cap to store spent test strips for disposal. The device may be turned on an off simply by removal and return of the cap.Type: ApplicationFiled: May 9, 2002Publication date: November 13, 2003Inventors: Devin McAllister, Lorin Olson, Borzu Sohrab
-
Publication number: 20030212344Abstract: Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g., an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip that include a biosensor and at least one skin-piercing element affixed to the test strip. The skin-piercing element conveys a biological fluid sample to a sensor element in the test strip. Systems are provided which include one or more test strip devices and a meter for making analyte concentration measurements. Methods for manufacturing and using the devices and systems are also provided.Type: ApplicationFiled: May 9, 2002Publication date: November 13, 2003Inventors: Vadim Yuzhakov, Devin McAllister, Lorin Olson, Koon-Wah Leong, Maria Teodorczyk
-
Publication number: 20030211619Abstract: The present invention provides continuous strips of testers in an individually-sealed water-impermeable packaging which maintains the testers in a sterile condition until used. The subject testers include a test strip sensor integrated with a microneedle for accessing and collecting a sample of physiological fluid and for measuring a chemical characteristic, such as target analyte concentration, of the sampled fluid. The present invention further provides cassettes of the subject strips for removable engagement with a meter for individually dispensing the testers and for facilitating the analysis of the sampled fluid. Also provided by the present invention are systems which include the subject strips and cassettes and such a meter. Methods of using the strips and cassettes are also provided, along with kits for practicing the subject methods.Type: ApplicationFiled: May 9, 2002Publication date: November 13, 2003Inventors: Lorin Olson, Devin McAllister
-
Publication number: 20030150745Abstract: Methods and devices for electrochemically detecting a change in the viscosity of a fluid are provided. In the subject methods, a fluid sample (e.g., a whole blood sample) is introduced into an electrochemical test strip's electrochemical cell using a micro-needle integrated into one of oppositely spaced apart working and reference electrodes. An electric potential is applied to the electrochemical cell to first achieve a steady state cell current. A decrease in the steady state cell current is then detected and related to a change in viscosity of the sample. In many embodiments, the sample is blood and the change in viscosity is related to the onset of coagulation in the blood sample, and often the PT of the blood sample. An electrochemical test strip includes an electrochemical cell and an integrated micro-needle. The electrochemical cell includes oppositely spaced apart working and reference electrodes and a reagent mixture (e.g., a redox couple and a coagulation catalyzing agent).Type: ApplicationFiled: August 23, 2002Publication date: August 14, 2003Inventors: Maria Teodorczyk, Ernest J. Kiser, Lorin P. Olson, Devin McAllister, Vadim V. Yuzhakov, Koon-wah Leong