Abstract: A single-reel zonal lacing system comprises a reel mechanism fixed to the upper, for example, the cuff or the tongue, and a separate cable for each zone. In a two-zone embodiment, a first cable engages the reel and extends across the elongate opening at least twice, and engages a multi-position retainer at an intermediate location. A second cable engages the reel and also extends across the elongate opening in at least two places. The cables are configured to be tensioned by the reel mechanism, and the effective length of the first cable is determined in part by the selected engagement position on the multi-position retainer, such that the relative tension in two zones may be adjusted. In one embodiment, only one end of the cables engage the reel mechanism, and the opposite end is anchored to the upper. In another embodiment, both ends of the cables engage the reel mechanism.