Patents by Inventor Devin Wolfe

Devin Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR SCREENING TO IDENTIFY THERAPEUTIC AGENTS FOR ALZHEIMER'S DISEASE AND USE THEREOF
    Publication number: 20160244805
    Abstract: Methods for treating Alzheimer's Disease (AD) using modulators of lysosomal activity are described herein. More particularly, methods described herein relate to the use and application of compounds or agents that enhance lysosomal activity for the treatment of AD. In a particular aspect, the method relates to the use and application of compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. Also described herein are methods and assays for screening to identify compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD.
    Type: Application
    Filed: February 22, 2016
    Publication date: August 25, 2016
    Inventors: Ralph A. NIXON, Ju-Hyun LEE, Devin WOLFE
  • Methods for screening to identify therapeutic agents for Alzheimer's disease and use thereof
    Patent number: 9265735
    Abstract: Methods for treating Alzheimer's Disease (AD) using modulators of lysosomal activity are described herein. More particularly, methods described herein relate to the use and application of compounds or agents that enhance lysosomal activity for the treatment of AD. In a particular aspect, the method relates to the use and application of compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. Also described herein are methods and assays for screening to identify compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: February 23, 2016
    Assignees: New York University, The Research Foundation for Mental Hygiene, Inc.
    Inventors: Ralph A. Nixon, Ju-Hyun Lee, Devin Wolfe
  • METHODS FOR SCREENING TO IDENTIFY THERAPEUTIC AGENTS FOR ALZHEIMER'S DISEASE AND USE THEREOF
    Publication number: 20120136064
    Abstract: Methods for treating Alzheimer's Disease (AD) using modulators of lysosomal activity are described herein. More particularly, methods described herein relate to the use and application of compounds or agents that enhance lysosomal activity for the treatment of AD. In a particular aspect, the method relates to the use and application of compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. Also described herein are methods and assays for screening to identify compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD.
    Type: Application
    Filed: November 30, 2011
    Publication date: May 31, 2012
    Inventors: Ralph A. Nixon, Ju-Hyun Lee, Devin Wolfe