Abstract: A catheter system includes a catheter with an elongate catheter body, a catheter tip coupled to a distal end of the catheter body, and at least one light-emitting element configured to emit light to excite flavin adenine dinucleotide (FAD) molecules. The catheter system further including at least one light sensor configured to sense a light emitted by the excited FAD molecules.

Abstract: An electrical implantable lead includes an elongated lead body having a plurality of lumens therein, including at least one linear lumen and at least one planar, non-linear lumen and a plurality of conductor cables disposed within the plurality of lumens. The electrical implantable lead further includes a terminal connector coupled to a proximal end of the lead body, the terminal connector being in electrical communication with at least one of the plurality of conductor cables. Further, the electrical implantable lead includes at least one electrode coupled to the lead body, the at least one electrode in electrical communication with at least one of the plurality of conductor cables. In accordance with various embodiments, the at least one non-linear lumen extends longitudinally along a portion of the lead body and includes a plurality or crests and a plurality of troughs.

Abstract: A device for collecting a tissue sample includes an outer needle extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough. The device also includes an inner needle extending longitudinally from a proximal end to a distal end and including an opening extending laterally in and along a length thereof. The inner needle is sized and shaped to be slidably received within the lumen of the outer needle and movable relative thereto between an insertion configuration, in which the opening is covered by the outer needle, to a tissue collecting configuration, in which the opening is exposed. In addition, the device includes a handle assembly for adjusting a throw length of the inner needle relative to the outer needle.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polyether polyurethane.

Abstract: A device for acquiring a tissue sample includes an outer sheath extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough; an inner needle extending longitudinally from a proximal end to a distal end and sized and shaped to be slidably received within the lumen of the outer sheath to be moved between an insertion configuration and a tissue collecting configuration; and a handle assembly connected to a proximal end of the outer sheath. The handle assembly includes a first port configured to be connected to a fluid flushing source and a second port configured to be connected to a collection element so that, when the inner needle is drawn proximally relative to the outer sheath to a sample collection configuration, the sample is flushable into the collection element.

Abstract: The present disclosure is directed to a valve structure that comprises a flexible structure having a distal portion configured for attachment to a first member and a proximal portion configured for attachment to a second member. The flexible structure is configured such that when the first member is extended distally relative to the second member, the flexible structure adopts a reduced width profile and such that when the first member is retracted proximally relative to the second member to a point of maximal retraction, the flexible structure adopts an expanded width profile, which is more resistant to deformation due to fluid pressure in a proximal direction than it is to deformation due to fluid pressure in a distal direction. The present disclosure is also directed to devices and methods pertaining to such a valve structure.

Abstract: An IS-4 terminal connector assembly includes three terminal electrodes positioned over an inner tubular member such that they are radially offset from one another. Each of the terminal ring electrodes are configured such that they can withstand both tensile and cyclical bending loads with minimal compromise in their outer geometry. Additionally, each of the terminal electrodes is configured such that they have both an inner and outer geometry that facilitates adequate insulation between a select terminal electrode and an adjacent conductor. Additionally, each of the terminal ring electrodes is configured such that they facilitate an external approach to staking a cable conductor.

Abstract: Implantable medical devices and method for making and using implantable medical devices are disclosed. An example implantable medical device may include a tubular body having a plurality of openings formed therein. A filter layer may be disposed along an outer surface of the tubular body. The filter layer may include a shape memory material. The filter layer may be capable of allowing fluids to pass therethrough and may be resistant to tissue ingrowth.

Abstract: An electrical implantable lead includes an elongated lead body having a plurality of lumens therein, including at least one linear lumen and at least one planar, non-linear lumen and a plurality of conductor cables disposed within the plurality of lumens. The electrical implantable lead further includes a terminal connector coupled to a proximal end of the lead body, the terminal connector being in electrical communication with at least one of the plurality of conductor cables. Further, the electrical implantable lead includes at least one electrode coupled to the lead body, the at least one electrode in electrical communication with at least one of the plurality of conductor cables. In accordance with various embodiments, the at least one non-linear lumen extends longitudinally along a portion of the lead body and includes a plurality or crests and a plurality of troughs.

Abstract: Tissue regions are treated using a multiple lead electrode probe. A plurality of electrodes may be disposed about an elongate shaft. The elongate shaft may be slidably disposed within a lumen of a delivery sheath. One or more probes including one or more electrically active regions may also be slidably disposed within the delivery sheath. The one or more probes may be configured to extend radially about the elongate shaft. The plurality of electrodes and the electrically active regions may be individually connected to a control and power unit through individual channels.

Abstract: An electrical implantable lead includes an elongated lead body having a plurality of lumens therein, including at least one linear lumen and at least one planar, non-linear lumen and a plurality of conductor cables disposed within the plurality of lumens. The electrical implantable lead further includes a terminal connector coupled to a proximal end of the lead body, the terminal connector being in electrical communication with at least one of the plurality of conductor cables. Further, the electrical implantable lead includes at least one electrode coupled to the lead body, the at least one electrode in electrical communication with at least one of the plurality of conductor cables. In accordance with various embodiments, the at least one non-linear lumen extends longitudinally along a portion of the lead body and includes a plurality or crests and a plurality of troughs.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polyether polyurethane.

Abstract: According to aspects of the present disclosure, a system may include a loading device including an exterior surface. The system may also include an expandable member mounted on the exterior surface of the loading device. The expandable member may be configured to selectively transition between a collapsed state and an expanded state. The system may also include a covering mounted on the expandable member. The covering may extend around the expandable member and the loading device. The loading device may be configured to position the expandable member and the covering for mounting on an exterior surface of an elongate introduction sheath.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polytetrafluoroethylene.

Abstract: Defibrillator lead designs and methods for manufacturing a lead having attachment between a fibrosis-limiting material covering, a shocking coil electrode, and an implantable lead body are disclosed herein. An electrode coil fitting is disposed within the shocking coil electrode. In an option, the fibrosis limiting material extends past the ends of the electrode coil, and is wrapped between the coil electrode and the electrode coil member.

Abstract: According to an aspect of the present disclosure, a medical device may include a deflation catheter assembly. The deflation catheter assembly may include a tubular member having an outer surface, an inner surface, and a central lumen defined by the inner surface. The deflation catheter assembly may also include a plurality of passages extending through a side of the tubular member and from the inner surface to the outer surface. The deflation catheter assembly may also include an anchoring member coupled to the tubular member. A distal portion of the tubular member may extend distal the anchoring member. The plurality of passages may be at the distal portion of the tubular member. The anchoring member may be configured to move between an unexpanded state and an expanded state. At least a portion of the anchoring member may protrude radially outwardly from the outer surface of the tubular member when the anchoring member is in the expanded state.

Abstract: According to aspects of the present disclosure, a retrieval catheter assembly for retrieving an intragastric balloon may include a tubular member configured to pass through a wall of the intragastric balloon. The retrieval catheter assembly may also include a retrieval member coupled to the tubular member and movable between an undeployed configuration and a deployed configuration. In the undeployed configuration the retrieval member may be substantially aligned with the tubular member. In the deployed configuration at least a portion of the retrieval member may diverge from the tubular member and may be configured to engage the wall of the intragastric balloon.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polytetrafluoroethylene.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from a non-conductive polycarbonate polyurethane polymer.

Abstract: Various embodiments concern leads having low peak MRI heating for improved MRI compatibility. Various leads include a lead body having at least one lumen, a proximal end configured to interface with an implantable medical device, and a distal end. Such leads can further include a conductor extending along at least a portion of the lead body within the at least one lumen and a defibrillation coil extending along an exterior portion of the lead body and in electrical connection with the conductor, wherein at least a section of the defibrillation coil is under longitudinal compression. The longitudinal compression can lower peak MRI heating along the defibrillation coil. The longitudinal compression may maintain circumferential contact between adjacent turns of the section of the defibrillation coil.