Patents by Inventor Devora Cohen-Karni

Devora Cohen-Karni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and Quantification of Hydroxymethylated Nucleotides in a Polynucleotide Preparation
    Publication number: 20150240310
    Abstract: Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 27, 2015
    Applicant: NEW ENGLAND BIOLABS, INC.
    Inventors: Jurate Bitinaite, Romualdas Vaisvila, Sriharsa Pradhan, Yu Zheng, Richard J. Roberts, Hang-Gyeong Chin, Devora Cohen-Karni, Christopher Noren, Elisabeth A. Raleigh, Geoffrey Wilson
  • Detection and quantification of hydroxymethylated nucleotides in a polynucleotide preparation
    Patent number: 9034597
    Abstract: Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: May 19, 2015
    Assignee: New England Biolabs, Inc.
    Inventors: Jurate Bitinaite, Romualdas Vaisvila, Sriharsa Pradhan, Yu Zheng, Richard J. Roberts, Devora Cohen-Karni, Christopher Noren, Elisabeth A. Raleigh, Geoffrey Wilson, Hang-Gyeong Chin
  • Detection and Quantification of Hydroxymethylated Nucleotides in a Polynucleotide Preparation
    Publication number: 20120156677
    Abstract: Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
    Type: Application
    Filed: August 25, 2010
    Publication date: June 21, 2012
    Applicant: NEW ENGLAND BIOLABS, INC.
    Inventors: Jurate Bitinaite, Romualdas Vaisvila, Sriharsa Pradhan, Yu Zheng, Richard J. Roberts, Devora Cohen-Karni, Christopher Noren, Elisabeth A. Raleigh, Geoffrey Wilson, Hang-Gyeong Chin