Patents by Inventor DEZHENG NING

DEZHENG NING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds as nuclear transport modulators and uses thereof
    Patent number: 12234226
    Abstract: Nuclear transport modulators are disclosed. The compounds can inhibit nuclear transporters such as the exportin-1 transporter. The compounds and pharmaceutical compositions comprising the compounds can be used to treat neurological diseases and cancer.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: February 25, 2025
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Zude Qi, Xianbo Liu, Dezheng Ning
  • COMPOUNDS AS NUCLEAR TRANSPORT MODULATORS AND USES THEREOF
    Publication number: 20230303530
    Abstract: Nuclear transport modulators are disclosed. The compounds can inhibit nuclear transporters such as the exportin-1 transporter. The compounds and pharmaceutical compositions comprising the compounds can be used to treat neurological diseases and cancer.
    Type: Application
    Filed: May 18, 2023
    Publication date: September 28, 2023
    Inventors: JIA-NING XIANG, ZUDE QI, XIANBO LIU, DEZHENG NING
  • Compounds as nuclear transport modulators and uses thereof
    Patent number: 11767313
    Abstract: Nuclear transport modulators are disclosed. The compounds can inhibit nuclear transporters such as the exportin-1 transporter. The compounds and pharmaceutical compositions comprising the compounds can be used to treat neurological diseases and cancer.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: September 26, 2023
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Zude Qi, Xianbo Liu, Dezheng Ning
  • Preparation and uses of reactive oxygen species scavenger derivatives
    Patent number: 11692008
    Abstract: Compounds of Formula (I)a or (I)b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: July 4, 2023
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • Reactive oxygen species scavengers and use for treating diseases
    Patent number: 11312703
    Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: April 26, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • COMPOUNDS AS NUCLEAR TRANSPORT MODULATORS AND USES THEREOF
    Publication number: 20210087177
    Abstract: Nuclear transport modulators are disclosed. The compounds can inhibit nuclear transporters such as the exportin-1 transporter. The compounds and pharmaceutical compositions comprising the compounds can be used to treat neurological diseases and cancer.
    Type: Application
    Filed: December 4, 2020
    Publication date: March 25, 2021
    Inventors: Jia-Ning Xiang, Zude Qi, Xianbo Liu, Dezheng Ning
  • REACTIVE OXYGEN SPECIES SCAVENGERS AND USE FOR TREATING DISEASES
    Publication number: 20210061791
    Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress.
    Type: Application
    Filed: November 12, 2020
    Publication date: March 4, 2021
    Inventors: JIA-NING XIANG, ZUDE QI, DEZHENG NING, XIANBO LIU
  • PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES
    Publication number: 20210047367
    Abstract: Compounds of Formula (I)a or (I)b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.
    Type: Application
    Filed: November 2, 2020
    Publication date: February 18, 2021
    Inventors: JIA-NING XIANG, ZUDE QI, DEZHENG NING, XIANBO LIU
  • Reactive oxygen species scavengers and use for treating diseases
    Patent number: 10889572
    Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: January 12, 2021
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • Preparation and uses of reactive oxygen species scavenger derivatives
    Patent number: 10858394
    Abstract: Compounds of Formula (I)a or (I)b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: December 8, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • PREPARATION AND USE OF REACTIVE OXYGEN SPECIES SCAVENGER
    Publication number: 20200199108
    Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 25, 2020
    Inventors: JIA-NING XIANG, ZUDE QI, DEZHENG NING, XIANBO LIU
  • PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES
    Publication number: 20200181194
    Abstract: Compounds of Formula (I)a or (I)b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.
    Type: Application
    Filed: February 10, 2020
    Publication date: June 11, 2020
    Inventors: JIA-NING XIANG, ZUDE QI, DEZHENG NING, XIANBO LIU