Patents by Inventor Dganit Bar

Dganit Bar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-HUMAN ATP6V1B2 ANTIBODIES AND USES THEREOF
    Publication number: 20250136708
    Abstract: Described herein are anti-human ATP6VIB2 antibodies. The antibodies can be used to target senescent cells. Thus, the anti-ATP6VIB2 antibodies would be useful in treating diseases and conditions associated with cellular senescence.
    Type: Application
    Filed: February 6, 2023
    Publication date: May 1, 2025
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Valery KRIZHANOVSKY, Nataly FREIZUS, Dganit BAR, Vered CARMON
  • Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation
    Publication number: 20040229886
    Abstract: This invention provides a method for the treatment of a subject in need of treatment for osteoarthritis comprising administering to said subject an amount of an inhibitor of spermidine biosynthesis sufficient to effect a substantial inhibition of spermidine biosynthesis. This invention also provides the use of an inhibitor of spermidine biosynthesis in the treatment of a subject in need of treatment of osteoarthritis in an amount sufficient to effect a substantial inhibition of spermidine biosynthesis This invention further provides a method of preparing a therapeutic composition for the treatment of a subject in need of a treatment for osteoarthritis and the invention further provides a method identifying an inhibitor of spermidine biosynthesis, whereby the inhibitor is a spermidine synthesis inhibitor.
    Type: Application
    Filed: February 24, 2004
    Publication date: November 18, 2004
    Applicant: Quark Biotech, Inc. & Shionogi Co., Ltd.
    Inventors: Dganit Bar, Elena Feinstein, Orit Segev
  • Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation
    Patent number: 6696454
    Abstract: This invention provides a method for the treatment of a subject in need of treatment for osteoarthritis comprising administering to said subject an amount of an inhibitor of spermidine biosynthesis sufficient to effect a substantial inhibition of spermidine biosynthesis. This invention also provides the use of an inhibitor of spermidine biosynthesis in the treatment of a subject in need of treatment of osteoarthritis in an amount sufficient to effect a substantial inhibition of spermidine biosynthesis. This invention further provides a method of preparing a therapeutic composition for the treatment of a subject in need of a treatment for osteoarthritis and the invention further provides a method of identifying an inhibitor of spermidine biosynthesis, whereby the inhibitor is a spermidine synthase inhibitor.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: February 24, 2004
    Assignees: Quark Biotech, Inc., Shionogi & Co., Ltd.
    Inventors: Dganit Bar, Elena Feinstein, Orit Segev
  • Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation
    Publication number: 20020160978
    Abstract: This invention provides a method for the treatment of a subject in need of treatment for osteoarthritis comprising administering to said subject an amount of an inhibitor of spermidine biosynthesis sufficient to effect a substantial inhibition of spermidine biosynthesis. This invention also provides the use of an inhibitor of spermidine biosynthesis in the treatment of a subject in need of treatment of osteoarthritis in an amount sufficient to effect a substantial inhibition of spermidine biosynthesis. This invention further provides a method of preparing a therapeutic composition for the treatment of a subject in need of a treatment for osteoarthritis and the invention further provides a method of identifying an inhibitor of spermidine biosynthesis, whereby the inhibitor is a spermidine synthase inhibitor.
    Type: Application
    Filed: December 12, 2001
    Publication date: October 31, 2002
    Inventors: Dganit Bar, Elena Feinstein, Orit Segev