Patents by Inventor Dharmendra Pratap Singh

Dharmendra Pratap Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREGNANE-OXIMINO-AMINOALKYLETHERS AND PROCESS FOR PREPARATION THEREOF, USEFUL AS ANTIDIABETIC AND ANTIDYSLIPIDEMIC AGENTS
    Publication number: 20160009752
    Abstract: The present invention relates to the synthesis of pregnane-oximino-aminoalkyl-ethers and their antidiabetic and antidyslipidemic activities. More particularly, the invention relates to the synthesis of compounds of formula 3 and biological profile thereof. Further the invention relates to compounds of formula 3 and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: January 24, 2014
    Publication date: January 14, 2016
    Inventors: Prem Chandra VERMA, Jyoti GUPTA, Dharmendra Pratap SINGH, Varsha GUPTA, Hari Narayan KUSHWAHA, Anamika MISRA, Neha RAHUJA, Rohit SRIVASTAVA, Natasha JAISWAL, Ashok Kumar KHANNA, Akhilesh Kumar TAMRAKAR, Shio Kumar SINGH, Anil Kumar DWIVEDI, Arvind Kumar SRIVASTAVA, Ram PRATAP
  • Process for preparing guggulsterones
    Patent number: 7365218
    Abstract: The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 ? hydroxy-16 ?, 17-oxido-5 pregnen-20-one, converting the 3 ? hydroxy-16?, 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidation to obtain desired guggulsterones viz. to 5, 17-(20)-cis and trans pregnadiene-3 ?, 16-diol of the formula Ia and Ib.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: April 29, 2008
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ram Pratap, Dharmendra Pratap Singh, Raghavendra Pal, Satyawan Singh
  • Process for preparing Guggulsterones
    Publication number: 20040186306
    Abstract: The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 &bgr; hydroxy-16 &agr;, 17-oxido-5 pregnen-20-one, converting the 3 &bgr; hydroxy-16&agr;, 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidation to obtain desired guggulsterones viz. to 5, 17-(20)-cis and trans pregnadiene-3 &bgr;, 16-diol of the formula Ia and Ib.
    Type: Application
    Filed: March 20, 2003
    Publication date: September 23, 2004
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Ram Pratap, Dharmendra Pratap Singh, Raghavendra Pal, Satyawan Singh