Abstract: A luminaire includes an elongated first housing, an elongated second housing, and a bracket. The elongated first housing supports a first light emitting device and includes a pair of sides and a first channel defined between the sides. The first housing includes a first aperture. The elongated second housing includes a pair of sides and a second channel defined between the sides. An end of the second housing is positioned adjacent an end of the first housing and includes a second aperture disposed proximate the first aperture. The bracket includes a first projection engageable with the first aperture and a second projection engageable with the second aperture. The bracket is positioned partially within the first channel and partially within the second channel. The bracket is coupled to the first housing by snap-fit engagement and the bracket is coupled to the second housing by snap-fit engagement.

Abstract: A light fixture includes a housing, a recessed channel, a light-emitting element, and a lens positioned over the light-emitting element. The housing includes a mounting surface. The recessed channel includes a bottom and a pair of side walls extending along the length of the mounting surface. The light-emitting element is coupled to the bottom of the recessed channel. The lens is positioned over the light-emitting element and removably retained between the pair of side walls.

Abstract: The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.

Abstract: A wall mounted light fixture includes a surface mount including a rear wall having a plurality of mounting openings, a top wall extending from the rear wall, and a bottom wall extending from the rear wall. The light fixture housing is connected to the surface mount and defines an interior portion. A light emitter is positioned in the interior portion of the housing. A lens is connected to the housing. A sensor assembly including a sensor housing and a sensor module is positioned at least partially in the sensor housing. The sensor assembly is operatively connected to the light emitter and the sensor housing is external to the light fixture housing.

Abstract: An illuminated vanity mirror includes a housing and a front mirror panel connected to the housing. A frame is connected to the housing and positioned behind the front mirror panel. A light emitter is connected to frame. The light emitter includes a plurality of LEDs facing away from the front mirror panel. The LEDs are positioned to direct emitted light toward the housing and the emitted light is redirected through the front mirror panel.

Abstract: A light fixture includes a housing and a light emitting element. The housing includes a lower edge and is configured to be recessed within a surface. The light emitting element is supported in the housing, and the light emitting element includes a planar surface spaced apart from the lower edge of the housing.

Abstract: A battery module includes a plurality of electrochemical cells and a structure including an upper portion configured to support a bottom portion of each of the plurality of electrochemical cells and a lower portion coupled to the upper portion. The lower portion includes a thermal management feature having at least one passage provided therein. The passage is configured for a thermal management fluid to pass therethrough to provide thermal management to the electrochemical cells of the battery module.

Abstract: A wall mounted light fixture includes a body at least partially defining a housing. The body has a first side facing an interior of the housing and a second side facing the exterior of the housing. The first side of the body has a plurality of front connecting features and the second side of the body has a plurality of rear connecting features. A light emitter is positioned in the interior of the housing and supported by the first side of the body. A lens is connected to at least one of the front connecting features. A mounting component is connected to at least one of the rear connecting features.

Abstract: A battery module includes a plurality of electrochemical cells and a structure including an upper portion configured to support a bottom portion of each of the plurality of electrochemical cells and a lower portion coupled to the upper portion. The lower portion includes a thermal management feature having at least one passage provided therein. The passage is configured for a thermal management fluid to pass therethrough to provide thermal management to the electrochemical cells of the battery module.

Abstract: A battery module includes a plurality of electrochemical cells and a structure including an upper portion configured to support a bottom portion of each of the plurality of electrochemical cells and a lower portion coupled to the upper portion. The lower portion includes a thermal management feature having at least one passage provided therein.

Abstract: Provided herein are novel panels of biomarkers for the diagnosis of autoimmune diseases, and methods and kits for detecting these biomarkers in samples of individuals suspected of having an autoimmune disease. Also provided are methods of monitoring the progression of an autoimmune disease and methods of monitoring the efficacy and side effects of a treatment for an autoimmune disease.

Abstract: Provided herein are novel panels of biomarkers for the diagnosis of autoimmune diseases, and methods and kits for detecting these biomarkers in samples of individuals suspected of having an autoimmune disease. Also provided are methods of monitoring the progression of an autoimmune disease and methods of monitoring the efficacy and side effects of a treatment for an autoimmune disease.

Abstract: Methods are provided for evaluating osteoarthritis (OA), for example for diagnosing OA, to confirm a diagnosis of OA, to assess or prognose progression of OA, determining the severity of a subject who has OA, and determining a subject's risk of developing OA in the future, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes determining an amount of activity (such as an amount of protein present or an amount of expression) of OA risk-related molecules, such as soluble vascular adhesion protein 1 (sVAP-1) or interleukin-15 (IL-15). Also provided are methods of identifying one or more compounds that alter the activity of an OA-related molecule, thereby identifying potential anti-osteoarthritis drugs.

Abstract: The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also relates to a method of inducing anti-HIV antibodies using same.

Abstract: The present invention relates to an isolated nucleic acid molecule having a sequence that encodes a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to a construct containing the nucleic acid molecule and to a host cell comprising same. Further, the invention relates to a method of producing a CD6 ligand.

Abstract: The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cells types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to the methods of screening componunds for their ability to inhibit that interaction.

Abstract: The present invention relates to a method of effecting site-specific cleavage of RNA and to an element and a factor responsible for such cleavage.