Abstract: Systems and methods for managing supply chain of products and services are disclosed herein. A system generates supply chain data based on historical data received from data sources corresponding to supply chain of product or service. Further, system extracts data entity and set of attributes from supply chain data, to determine semantically related data entities. Furthermore, system determines use case corresponding to management of supply chain, based on semantically related data entities. Additionally, system predicts, risk or priority associated with product or service in the supply chain, to generate risks and alerts, based on prediction. Further, system assigns critical and high-priority use case to one or more agents based on a performance score of the one or more agents. Furthermore, system provides insights and suggestions for managing the supply chain of product or service at regional level and global level of supply chain.