Patents by Inventor Dhruv Sarin

Dhruv Sarin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blood substitutes and uses thereof
    Patent number: 9387152
    Abstract: The invention relates to blood substitute compositions, and methods of use thereof. Described herein are compositions in which hemoglobin is maintained substantially in the reduced form of hemoglobin as opposed to the oxidized methemoglobin form through inclusion of an oxido-reductase enzyme and reducing agent within a vesicle with the hemoglobin. The vesicles additionally can comprise a dismutase, a catalase, and an electron acceptor, each of which contribute to either the maintenance of hemoglobin in the active oxygen carrying state or provide a benefit not achieved with free hemoglobin.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: July 12, 2016
    Assignee: THE GENERAL HOSPITAL CORPORATION
    Inventors: Martin L. Yarmush, Eric Yang, Tali Konry, Erkin Seker, Dhruv Sarin, Prakash Rai
  • BLOOD SUBSTITUTES AND USES THEREOF
    Publication number: 20130307170
    Abstract: The invention relates to blood substitute compositions, and methods of use thereof. Described herein are compositions in which hemoglobin is maintained substantially in the reduced form of hemoglobin as opposed to the oxidized methemoglobin form through inclusion of an oxido-reductase enzyme and reducing agent within a vesicle with the hemoglobin. The vesicles additionally can comprise a dismutase, a catalase, and an electron acceptor, each of which contribute to either the maintenance of hemoglobin in the active oxygen carrying state or provide a benefit not achieved with free hemoglobin.
    Type: Application
    Filed: June 28, 2011
    Publication date: November 21, 2013
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Martin L. Yarmush, Eric Yang, Tali Konry, Erkin Seker, Dhruv Sarin, Prakash Rai