Abstract: The present invention discloses a robotic assisted system for ophthalmic surgery, comprising a first driving unit, a second driving unit and a third driving unit, wherein the three driving units can respectively complete the movement in three dimensions, the first driving unit is connected with the second driving unit, the second driving unit is connected with the third driving unit, and an instrument is arranged on the third driving unit; during operating, the third driving unit can drive the instrument assembly to move, the second driving unit can drive the third driving unit and instruments thereon to move, and the first driving unit can drive the second driving unit, the third driving unit on the second driving unit and the instruments on the third driving unit to move; the accurate control on the instruments can be completed by controlling the three different driving units.

Abstract: Embodiments of this disclosure relate to techniques and systems for preparing modified cells evoking reduced immunogenic responses and application thereof. For example, hypo-immunogenic (e.g., decreased immunogenicity) and compatible stem cells may be obtained by a disruption in Transporter associated with antigen presentation 1 (TAP1) or TAP-associated glycoprotein (TAPBP) genes while maintaining normal pluripotency, karyotypes, and differentiation ability of these cells.

Abstract: The present disclosure describes composition, methods, and systems associated with a genetically modified stem cell. The modified stem cell includes a reduced amount of Major Histocompatibility Complex II (MHC II) as compared to a corresponding wild-type cell. Further, the modified cell has decreased immunogenicity as compared to the corresponding wild-type cell.