Patents by Inventor Di-Hewi Hsu

Di-Hewi Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing membrane vesicles
    Publication number: 20040241176
    Abstract: The present invention relates to methods of preparing biological material, for use in various experimental, diagnostic or therapeutic uses, including immunotherapy treatment or prophylaxy of tumors. More particularly, the present invention relates to methods of preparing membrane vesicles (in particular exosomes) released by various types of mammalian cells, comprising diafiltration and/or density cushion centrifugation. The invention also provides novel methods for characterizing and analyzing exosome preparations, which can be used in quality control assay for the purpose of pharmaceutical product production. The invention is suitable to produce pharmaceutical grade preparations of such membrane vesicles and to fully characterize said preparations, for use in human beings.
    Type: Application
    Filed: February 9, 2001
    Publication date: December 2, 2004
    Applicant: AP CELLS. INC.
    Inventors: Henry Lamparski, Curtis Ruegg, Jean-Bernard Le-Pecq, Di-Hewi Hsu, Jenq-Yuan Yao
  • Methods of producing membrane vesicles
    Patent number: 6812023
    Abstract: The present invention relates to methods of preparing biological material, for use in various experimental, diagnostic or therapeutic uses, including immunotherapy treatment or prophylaxy of tumors. More particularly, the present invention relates to methods of preparing membrane vesicles (in particular exosomes) released by various types of mammalian cells, comprising diafiltration and/or density cushion centrifugation. The invention also provides novel methods for characterizing and analyzing exosome preparations, which can be used in quality control assay for the purpose of pharmaceutical product production. The invention is suitable to produce pharmaceutical grade preparations of such membrane vesicles and to fully characterize said preparations, for use in human beings.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: November 2, 2004
    Assignee: Anosys, Inc.
    Inventors: Henry Lamparski, Curtis Ruegg, Jean-Bernard Le Pecq, Di-Hewi Hsu, Jenq Yuan Yao