Patents by Inventor Di Lu

Di Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240002500
    Abstract: Provided is an anti-TIGIT antibody or an antigen-binding fragment thereof. The antibody or the antigen-binding fragment thereof has a higher affinity for TIGIT, has functional characteristics in a plurality of aspects, and may be used alone or in combination with other reagents for treating cancers, and diseases related to immunity and inflammation.
    Type: Application
    Filed: November 19, 2021
    Publication date: January 4, 2024
    Inventors: Di LU, Yongting HUO, Lisheng LU, Zhe HAN, Peipei HU, Jingjing TU, Chan ZHANG
  • Publication number: 20230397831
    Abstract: A wearable probe includes a sensor module and a control module. The sensor module includes a transmission source to transmit signals into the tissue at a source position, and two detectors to detect a result of the signals, the two detectors including a first detector positioned at a first separation distance from the source position and a second detector positioned at a second separation distance from the source position. The control module includes a controller and a battery to power the controller and the sensor module. The control module includes a processor, a memory including instructions, and a communications interface. The instructions cause the processor to control the sensor module to transmit signals into the tissue and detect results of the signals with the at least two detectors, receive the detected results, store the detected results in the memory, and transmit the detected results to a remote device.
    Type: Application
    Filed: October 22, 2021
    Publication date: December 14, 2023
    Inventors: Mitchell Pet, Matthew MacEwan, John Rogers, Changsheng Wu, Di Lu, Wubin Bai, Hexia Guo, Shuo Li, Hany Arafa
  • Publication number: 20230385551
    Abstract: A caption of a multimodal message (e.g., social media post) can be identified as a named entity using an entity recognition system. The entity recognition system can use a visual attention based mechanism to generate a visual context representation from an image and caption. The system can use the visual context representation to identify one or more terms of the caption as a named entity.
    Type: Application
    Filed: May 23, 2023
    Publication date: November 30, 2023
    Inventors: Di Lu, Leonardo Ribas Machado das Neves, Vitor Rocha de Carvalho, Ning Zhang
  • Publication number: 20230312709
    Abstract: The present application relates to the field of biomedicines, in particular to an antibody targeting CD47 and an application thereof. The anti-CD47 antibody provided by the present application may specifically bind to tumor cells, block the signal of human SIRP? and human CD47, and promote the phagocytosis of the tumor cells by macrophages. The antibody has high affinity, strong specificity, and good safety. The red blood cell (RBC) agglutination is not caused, and it shows very weak binding to RBC and platelets.
    Type: Application
    Filed: December 22, 2021
    Publication date: October 5, 2023
    Inventors: Yongting HUO, Lisheng LU, Jingjing TU, Di LU, Chan ZHANG, Jiaqing YAN
  • Publication number: 20230277303
    Abstract: Provided are systems and methods for wireless, LCR-based, passive sensor systems for catheter or other implantable deployment using collapsible electromechanics. Each sensor system includes a deformable coil and a capacitive pressure sensor, collectively forming a LCR circuit having a self-resonant frequency. Multiple sensor systems may be implanted in a collapsible artificial valve to non-invasively detect the status of the collapsible artificial valve. Specifically, when the collapsible artificial valve is implanted in a mammal subject, antennas may be disposed on the skin of the mammal subject to wirelessly measure the self-resonant frequencies of the LCR circuits of the sensor systems. Thus, the blood pressure of the mammal subject may be calculated based on the self-resonant frequencies measured by the antenna, and the status of the collapsible artificial valve may be determined based on the blood pressure.
    Type: Application
    Filed: September 7, 2021
    Publication date: September 7, 2023
    Inventors: John A. Rogers, Anthony R. Banks, Di Lu
  • Patent number: 11687720
    Abstract: A caption of a multimodal message (e.g., social media post) can be identified as a named entity using an entity recognition system. The entity recognition system can use a visual attention based mechanism to generate a visual context representation from an image and caption. The system can use the visual context representation to identify one or more terms of the caption as a named entity.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: June 27, 2023
    Assignee: Snap Inc.
    Inventors: Di Lu, Leonardo Ribas Machado das Neves, Vitor Rocha de Carvalho, Ning Zhang
  • Patent number: 11530036
    Abstract: A fixed-wing aerial underwater vehicle includes a shell component, a flight component and a pneumatic buoyancy component. The flight component includes a fixed wing and rotors, and the fixed wing and the rotors are mounted in the shell component. The pneumatic buoyancy component includes an air bladder and an inflation and deflation portion, and the inflation and deflation portion can inflate and deflate the air bladder. The air bladder is installed on the shell component, a containing space is formed in the shell component, and the inflation and deflation portion is partially or entirely installed in the containing space. Each rotor includes a rotor supporting rod, a motor base, a motor and a propeller, which are sequentially connected. A control method for the fixed-wing aerial underwater vehicle mentioned above is further provided.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: December 20, 2022
    Assignee: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Zheng Zeng, Lian Lian, Di Lu, Ping Ren, Xiafei Ma
  • Patent number: 11514278
    Abstract: Embodiments of the present invention are directed to facilitating data preprocessing for machine learning. In accordance with aspects of the present disclosure, a training set of data is accessed. A preprocessing query specifying a set of preprocessing parameter values that indicate a manner in which to preprocess the training set of data is received. Based on the preprocessing query, a preprocessing operation is performed to preprocess the training set of data in accordance with the set of preprocessing parameter values to obtain a set of preprocessed data. The set of preprocessed data can be provided for presentation as a preview. Based on an acceptance of the set of preprocessed data, the set of preprocessed data is used to train a machine learning model that can be subsequently used to predict data.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: November 29, 2022
    Assignee: SPLUNK Inc.
    Inventors: Manish Sainani, Sergey Slepian, Di Lu, Adam Oliner, Jacob Leverich, Iryna Vogler-Ivashchanka, Iman Makaremi
  • Patent number: 11469077
    Abstract: A microwave plasma chemical vapor deposition device for diamond synthesis. A microwave source generates a microwave signal, and a resonant cavity receives a plurality of process gases. The microwave signal is spread in a first mode at a first waveguide. A mode conversion antenna converts the first mode of the microwave signal into a second mode that is spread at a second waveguide. A coupling conversion cavity receives and transmits the microwave signal in the second mode to the mode conversion antenna thereby converting the second mode of the microwave signal into a third mode. A medium viewport receives the microwave signal in the third mode and transmits to the resonant cavity which enables the microwave signal to excite and discharge the process gases to form spherical plasma, carbon containing groups and atomic hydrogen thereby depositing a diamond film on a seed.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: October 11, 2022
    Assignee: FD3M, Inc.
    Inventors: Yi Ma, Matthew L. Scullin, Jinhua Zhu, Jianxin Wu, Yong Miao, Di Lu, Yonggan Ai, Christopher E. Griffin
  • Patent number: 11194794
    Abstract: Embodiments of the present invention are directed to facilitating search input recommendations. In accordance with aspects of the present disclosure, a set of events determined from raw machine data is obtained. The events are analyzed to generate a temporal map associated with the set of events. Generally, the temporal map associates candidate terms with temporally related terms that occur within a period of time corresponding with the candidate terms. A search term input into a search field is received. Based on the input search term, the temporal map is used to identify one or more temporally related term recommendations.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: December 7, 2021
    Assignee: Splunk Inc.
    Inventors: Adam Jamison Oliner, Hongyang Zhang, Sergey Slepian, Di Lu, XiaoYu Jia, Peter Chongjin Kim, Manish Sainani
  • Publication number: 20210369621
    Abstract: The present application relates to a pregabalin sustained release composition, comprising: (a) an active ingredient; (b) a matrix-forming agent; (c) a swelling agent; (d) a gelling agent; and optionally a filler. The pregabalin sustained release composition provided in the present application can rapidly swell in volume when exposed to aqueous medium until exceeding the diameter of human gastric pyloric (13 mm). It thereby prolongs the gastric emptying time to increase the retention time of pregabalin in the stomach and enhances absorption of pregabalin in the small intestine and ascending colon. Moreover, the pregabalin sustained release composition provided herein achieves a sustained release for 24 h, which allows QD (once a day) administration, reduces administration number, and improves patient compliance.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 2, 2021
    Applicant: Beijing Tide Pharmaceutical Co., Ltd.
    Inventors: Zhaolu Zhu, Yun Wu, Di Lu, Yanping Zhao, Liying Zhou, Yanan Liu
  • Patent number: 11120326
    Abstract: Example implementations are directed to systems and methods for a context aware conversational agent for self-learning. In an example implementation, a method includes generating a journaling model based on activity data and engagement data associated with one or more tasks of a user. The journaling model uses machine-learning to identify a context pattern using the activity data, and maps performance associated with the one or more tasks based at least on the engagement data. The method adaptively provides a prompt to gather additional engagement data based on the context pattern in view of real-time activity data, where the prompt is generated based on the journaling model. The journaling model is updated based on the additional engagement data.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: September 14, 2021
    Assignee: FUJIFILM Business Innovation Corp.
    Inventors: Daniel Avrahami, Jennifer Marlow, Rafal Kocielnik, Di Lu
  • Publication number: 20210256213
    Abstract: A caption of a multimodal message (e.g., social media post) can be identified as a named entity using an entity recognition system. The entity recognition system can use a visual attention based mechanism to generate a visual context representation from an image and caption. The system can use the visual context representation to identify one or more terms of the caption as a named entity.
    Type: Application
    Filed: May 3, 2021
    Publication date: August 19, 2021
    Inventors: Di Lu, Leonardo Ribas Machado das Neves, Vitor Rocha de Carvalho, Ning Zhang
  • Publication number: 20210192395
    Abstract: Disclosed herein is a computer-implemented tool that facilitates data analysis by use of machine learning (ML) techniques. The tool cooperates with a data intake and query system and provides a graphical user interface (GUI) that enables a user to train and apply a variety of different ML models on user-selected datasets of stored machine data. The tool can provide active guidance to the user, to help the user choose data analysis paths that are likely to produce useful results and to avoid data analysis paths that are less likely to produce useful results.
    Type: Application
    Filed: March 3, 2021
    Publication date: June 24, 2021
    Inventors: Manish Sainani, Sergey Slepian, Iman Makaremi, Adam Jamison Oliner, Jacob Leverich, Di Lu
  • Patent number: 11017173
    Abstract: A caption of a multimodal message (e.g., social media post) can be identified as a named entity using an entity recognition system. The entity recognition system can use a visual attention based mechanism to generate a visual context representation from an image and caption. The system can use the visual context representation to identify one or more terms of the caption as a named entity.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 25, 2021
    Assignee: Snap Inc.
    Inventors: Di Lu, Leonardo Ribas Machado das Neves, Vitor Rocha de Carvalho, Ning Zhang
  • Patent number: 10956834
    Abstract: Disclosed herein is a computer-implemented tool that facilitates data analysis by use of machine learning (ML) techniques. The tool cooperates with a data intake and query system and provides a graphical user interface (GUI) that enables a user to train and apply a variety of different ML models on user-selected datasets of stored machine data. The tool can provide active guidance to the user, to help the user choose data analysis paths that are likely to produce useful results and to avoid data analysis paths that are less likely to produce useful results.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: March 23, 2021
    Assignee: SPLUNK INC.
    Inventors: Manish Sainani, Sergey Slepian, Iman Makaremi, Adam Jamison Oliner, Jacob Leverich, Di Lu
  • Patent number: 10957915
    Abstract: The disclosure includes a platinum-based alloy catalyst and a preparation method thereof, a membrane electrode and a fuel cell. The method for preparing the platinum-based alloy catalyst comprises the following steps: (1) preparing nano-sized alloy particles of platinum and 3d transition metal; (2) carrying out acid treatment on the alloy particles prepared in step (1); and (3) annealing the alloy particles treated in step (2). The size of the platinum-based alloy particles is controlled, an atom number ratio of platinum to transition metal in the platinum-based alloy is controlled, and then etching and dissolution of acid is combined so that an atom number ratio of platinum to transition metal is further controlled, subsequently annealing is carried out at high temperature. The prepared platinum-based alloy catalyst improves the stability and durability of the platinum-based alloy catalyst, which supports the large-scale application of the platinum-based alloy catalyst in the fuel cell.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: March 23, 2021
    Assignee: QINGDAO CHUANGQI XSNNENG CATALYSIS TECHNOLOGY CO., LTD
    Inventors: Jie Zhang, Xin Liang, Hong Zhao, Sung Lai Jimmy Yun, Di Lu
  • Publication number: 20210061458
    Abstract: A fixed-wing aerial underwater vehicle includes a shell component, a flight component and a pneumatic buoyancy component. The flight component includes a fixed wing and rotors, and the fixed wing and the rotors are mounted in the shell component. The pneumatic buoyancy component includes an air bladder and an inflation and deflation portion, and the inflation and deflation portion can inflate and deflate the air bladder. The air bladder is installed on the shell component, a containing space is formed in the shell component, and the inflation and deflation portion is partially or entirely installed in the containing space. Each rotor includes a rotor supporting rod, a motor base, a motor and a propeller, which are sequentially connected. A control method for the fixed-wing aerial underwater vehicle mentioned above is further provided.
    Type: Application
    Filed: January 10, 2018
    Publication date: March 4, 2021
    Applicant: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Zheng ZENG, Lian LIAN, Di LU, Ping REN, Xiafei MA
  • Publication number: 20210020955
    Abstract: The disclosure includes a platinum-based alloy catalyst and a preparation method thereof, a membrane electrode and a fuel cell. The method for preparing the platinum-based alloy catalyst comprises the following steps: (1) preparing nano-sized alloy particles of platinum and 3d transition metal; (2) carrying out acid treatment on the alloy particles prepared in step (1); and (3) annealing the alloy particles treated in step (2). The size of the platinum-based alloy particles is controlled, an atom number ratio of platinum to transition metal in the platinum-based alloy is controlled, and then etching and dissolution of acid is combined so that an atom number ratio of platinum to transition metal is further controlled, subsequently annealing is carried out at high temperature. The prepared platinum-based alloy catalyst improves the stability and durability of the platinum-based alloy catalyst, which supports the large-scale application of the platinum-based alloy catalyst in the fuel cell.
    Type: Application
    Filed: March 22, 2019
    Publication date: January 21, 2021
    Applicant: QINGDAO CHUANGQI XINNENG CATALYSIS TECHNOLOGY CO., LTD
    Inventors: Jie ZHANG, Xin LIANG, Hong ZHAO, Sung Lai Jimmy YUN, Di LU
  • Patent number: D1003837
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: November 7, 2023
    Inventor: Di Lu