Patents by Inventor Di Xiang

Di Xiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9339528
    Abstract: The invention provides a use of the interleukin-1 receptor antagonist protein for preparing a medicament for preventing or treating epithelium trauma of the intestinal mucosa, wherein the protein is selected from: (a) a protein having an amino acid sequence as shown in SEQ ID NO: 1; (b) a protein which has a sequence having at least 70% homology with the amino acid sequence in the (a) and has the effect of preventing or treating epithelium trauma of the intestinal mucosa. The invention also provides a pharmaceutical composition comprising the protein (a) or (b) as the active component.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: May 17, 2016
    Assignee: GENERAL REGENERATIVES, LTD.
    Inventors: Wei Han, Di Xiang, Zhenqian Wu
  • Publication number: 20120322723
    Abstract: The invention provides a use of the interleukin-1 receptor antagonist protein for preparing a medicament for preventing or treating epithelium trauma of the intestinal mucosa, wherein the protein is selected from: (a) a protein having an amino acid sequence as shown in SEQ ID NO: 1; (b) a protein which has a sequence having at least 70% homology with the amino acid sequence in the (a) and has the effect of preventing or treating epithelium trauma of the intestinal mucosa. The invention also provides a pharmaceutical composition comprising the protein (a) or (b) as the active component.
    Type: Application
    Filed: October 26, 2010
    Publication date: December 20, 2012
    Inventors: Wei Han, Di Xiang, Zhenqian Wu
  • Patent number: 8323635
    Abstract: The present invention relates to uses of interleukin-1 receptor antagonist (IL-1Ra) in promoting bone marrow regeneration, increasing peripheral white blood cells, and increasing platelet levels in subjects if administered prior to treatment with chemotherapeutic agents. Thus, particular embodiments of the invention are directed to uses of IL-1Ra as an adjuvant or ancillary therapy to alleviate the hematopoietic toxicities associated with chemotherapy.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: December 4, 2012
    Assignee: General Regeneratives, Ltd.
    Inventors: Wei Han, Jing Zhang, Di Xiang, Shunying Zhu
  • Publication number: 20110236305
    Abstract: CXCR3 agonists, including natural CXCR3 ligands, promote bone marrow regeneration, increase peripheral white blood cells, and increase survival if administered prior to treatment of a subject with chemotherapy or radiotherapy. Similar effects are obtained by administering an CXCR3 antagonists following chemotherapy radiotherapy. Compositions and methods are presented for the treatment of cancer and bone marrow diseases.
    Type: Application
    Filed: March 30, 2011
    Publication date: September 29, 2011
    Inventors: Wei Han, Huili Lu, Di Xiang
  • Patent number: 7943131
    Abstract: CXCR3 agonists, including natural CXCR3 ligands, promote bone marrow regeneration, increase peripheral white blood cells, and increase survival if administered prior to treatment of a subject with chemotherapy or radiotherapy. Similar effects are obtained by administering an CXCR3 antagonists following chemotherapy radiotherapy. Compositions and methods are presented for the treatment of cancer and bone marrow diseases.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: May 17, 2011
    Assignee: General Regeneratives Holdings, Inc.
    Inventors: Wei Han, Huili Lu, Di Xiang
  • Publication number: 20100254937
    Abstract: The present invention relates to uses of interleukin-1 receptor antagonist (IL-1Ra) in promoting bone marrow regeneration, increasing peripheral white blood cells, and increasing platelet levels in subjects if administered prior to treatment with chemotherapeutic agents. Thus, particular embodiments of the invention are directed to uses of IL-1Ra as an adjuvant or ancillary therapy to alleviate the hematopoietic toxicities associated with chemotherapy.
    Type: Application
    Filed: November 14, 2007
    Publication date: October 7, 2010
    Applicant: GENERAL REGENERATIVES; LTD.
    Inventors: Wei Han, Jing Zhang, Di Xiang, Shunying Zhu
  • Publication number: 20100080756
    Abstract: CXCR3 agonists, including natural CXCR3 ligands, promote bone marrow regeneration, increase peripheral white blood cells, and increase survival if administered prior to treatment of a subject with chemotherapy or radiotherapy. Similar effects are obtained by administering an CXCR3 antagonists following chemotherapy radiotherapy. Compositions and methods are presented for the treatment of cancer and bone marrow diseases.
    Type: Application
    Filed: September 23, 2009
    Publication date: April 1, 2010
    Inventors: Wei Han, Huili Lu, Di Xiang
  • Patent number: 4961988
    Abstract: This invention relates to a general packing of expanded graphite and the process for production thereof. The packing mainly includes vermiform laminae of expanded graphite and auxiliary materials, which is characterized by the embedment of the auxiliary materials into the vermiform graphite laminae, the bonding of the auxiliary materials to the vermiform graphite laminae with organic adhesives. The process for producing of the packing comprises the treatment of graphite with strong acid to produce interlaminar compound followed by transient expansion of treated graphite to become vermiform and the combination of vermiform graphite laminae with the auxiliary materials to produce packing. Wherein the above mentioned vermiform laminae of expanded graphite are bonded to the auxiliary materials with organic adhesives, and the auxiliary materials are embedded between the vermiform laminae of expanded graphite.
    Type: Grant
    Filed: September 27, 1988
    Date of Patent: October 9, 1990
    Assignee: Zhejiang CI XI Seal Material Factory
    Inventor: Di Xiang Zhu