Abstract: Provided herein are compositions and methods of modulating myeloid cell-mediated killing of cancer cells and modulating the activity of myeloid cell immune checkpoint inhibitors. Also provided herein are methods of screening for modulators of myeloid cell-mediated killing of cancer cells and modulators of myeloid cell immune checkpoint inhibitors.

Abstract: A battery module includes a cell pack, a first structure, and a first wiring harness, where the cell pack includes a plurality of cells; the first structure includes a first surface facing the cell pack, and a second surface facing away from the first surface; the first structure further includes a first conductor disposed on the second surface and electrically connected to the cell pack; when viewed along a first direction perpendicular to the second surface, the first structure has a portion overlapping with the cell pack; when viewed along the first direction, the first structure includes a first region connected to the cell pack, and the first conductor is disposed between a first end surface of the first structure and the first region; and the first wiring harness is connected to the first conductor.

Abstract: A battery pack includes a housing assembly, a cell assembly, a first circuit board, a first heat sink, a first structural member, and a first insulator. The cell assembly includes a cell. The cell includes a cell housing, an electrode assembly, and an electrode terminal connected to the electrode assembly and led out from the cell housing. The first circuit board is disposed in the housing assembly and connected to the electrode terminal. The first heat sink is disposed in the housing assembly. The first structural member is disposed between the first circuit board and the first heat sink. An outer surface of the first structural member is provided with an insulating material. At least a part of the first insulator is disposed between the first structural member and the first heat sink, and the first structural member and the first heat sink are bonded by the first insulator.

Abstract: A battery pack includes a housing assembly, and a cell module and a first electrical connection portion accommodated in the housing assembly. The cell module includes a plurality of battery cells stacked in a first direction. The housing assembly includes a first wall and a second wall disposed opposite to each other in the first direction, the housing assembly is provided with an opening. The first electrical connection portion includes a first part and a second part, where the first part is electrically connected to the plurality of battery cells. The first part has a first edge, and the second part is connected to the first edge and disposed within the housing assembly. The second part is configured to connect to an external testing apparatus. The second part has a length greater than a distance between the first edge and the first wall in the first direction.

Abstract: The embodiments of the present disclosure provide a dynamic image quality video playing method, apparatus, electronic device and storage medium. The method includes: receiving a switch command for a video information stream, the switch command being for switching a target video played in the video information stream; determining an image quality selection strategy based on the switch command, and video information of the target video corresponding to the switch command, the image quality selection strategy being for characterizing image quality levels when playing a video to be played in the video information stream in different network conditions; and determining a target image quality level based on the image quality selection strategy and a current network condition, and playing, based on the target image quality level, the video to be played in the video information stream.

Abstract: A battery pack includes an upper shell, a lower shell, a battery cell assembly, a circuit board and a first component. The lower shell is provided with a battery cavity, the battery cell assembly is disposed in the battery cavity, the circuit board is connected to the battery cell assembly, the circuit board is located between the upper shell and the lower shell, the first component is provided with a first through hole running through the first component, the first through hole is located between the circuit board and the battery cell assembly, and the first through hole communicates with external air.

Abstract: A jelly-roll battery cell includes a first electrode plate, a second electrode plate, and a separator, and includes a central region enclosed by the first electrode plate, the second electrode plate, and the separator, and has a thickness direction. The first electrode plate includes: a first current collector, where the first current collector includes a first surface and a second surface opposite to the first surface, and the first surface is closer to the central region than the second surface; a first section; and a second section, where a first tab is disposed on the first surface in the second section. The second electrode plate includes a second tab whose first side is on the second electrode plate. The first end, the first tab, and the second tab do not overlap in a thickness direction.

Abstract: A shear force actuator is described, including: two substantially parallel first structural components disposed along a first axis; a plurality of substantially parallel second structural components disposed between and bridging the two first structural components; a plurality of joint sections each joining the second structural component with the first structural components at an oblique angle of between 0 and 90 degrees to define a plurality of cells, each capable of being connected with a fluid inflation or deflation source; an elastic surface covering the remaining surfaces of the cells in a fluid-tight manner, wherein at least one of the joint section, the first structural components, and the second structural components is elastic so that cell collapses upon removal of fluid from the cell to generate a linear force along the first axis.

Abstract: A shear force actuator is described, including: two substantially parallel first structural components disposed along a first axis; a plurality of substantially parallel second structural components disposed between and bridging the two first structural components; a plurality of joint sections each joining the second structural component with the first structural components at an oblique angle of between 0 and 90 degrees to define a plurality of cells, each capable of being connected with a fluid inflation or deflation source; an elastic surface covering the remaining surfaces of the cells in a fluid-tight manner, wherein at least one of the joint section, the first structural components, and the second structural components is elastic so that cell collapses upon removal of fluid from the cell to generate a linear force along the first axis.

Abstract: Embodiments of the disclosure concern methods and compositions related to treatment of diabetes and/or related conditions using cell therapy. In specific embodiments, cells that lacked the ability to produce insulin are exposed to one or more particular agents that render the cells to have the ability to produce insulin, and these cells are provided to an individual in need thereof. In a specific embodiment, the agent(s) are Wnt5a, FGF7, WNT3a, HGF, THBS2, IGF1, PDPN, LIF, endocan, SERPINF1, EGF, or a combination thereof.

Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.

Abstract: A soft robotic device with one or more sensors is described. The sensor may be embedded in the soft body of the soft robotic device, attached to the soft body of the soft robotic device, or otherwise linked to the soft body of the soft robotic device.

Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.

Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.

Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.

Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.

Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.

Abstract: A soft robotic device with one or more sensors is described. The sensor may be embedded in the soft body of the soft robotic device, attached to the soft body of the soft robotic device, or otherwise linked to the soft body of the soft robotic device.

Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.

Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.