Patents by Inventor Diana Alvarez Arias

Diana Alvarez Arias has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20230383298
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: January 3, 2023
    Publication date: November 30, 2023
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosuppression by tumor cells
    Patent number: 11597934
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: March 7, 2023
    Assignees: DANA FARBER CANCER INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Combination Therapies with Anti-CD38 Antibodies and PARP or Adenosine Receptor Inhibitors
    Publication number: 20220275090
    Abstract: This invention relates to a methods and compositions for treating a disease by administering a combination therapy comprising an anti-CD38 antibody and a poly ADP ribose polymerase inhibitor (PARPi); an anti-CD38 antibody and an adenosine receptor antagonist; or an anti-CD38 antibody, a PARPi and an adenosine receptor antagonist, to a subject (e.g., a human patient) in need thereof.
    Type: Application
    Filed: February 17, 2022
    Publication date: September 1, 2022
    Inventor: Diana Alvarez Arias
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20210139914
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 13, 2021
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosupression by tumor cells
    Patent number: 10876120
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: December 29, 2020
    Assignees: DANA-FARBER CANCER INSTITUTE, INC, THE GENERAL HOSPITAL CORPORATION
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20180327750
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: April 3, 2018
    Publication date: November 15, 2018
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosupression by tumor cells
    Patent number: 9944931
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: April 17, 2018
    Assignees: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20160122766
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: June 10, 2014
    Publication date: May 5, 2016
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias