Abstract: Disclosed herein are compositions, uses, and methods for treatment of prostate cancers.

Abstract: Disclosed herein are compositions, uses, and methods for treatment of ovarian cancers. In one aspect, provided herein is a composition or medical preparation comprising at least one RNA, wherein the at least one RNA encodes the following amino acid sequences: (i) an amino acid sequence comprising claudin 6 (CLDN6), an immunogenic variant thereof, or an immunogenic fragment of the CLDN6 or the immunogenic variant thereof; (ii) an amino acid sequence comprising p53, an immunogenic variant thereof, or an immunogenic fragment of the p53 or the immunogenic variant thereof; and (iii) an amino acid sequence comprising Preferentially Expressed Antigen In Melanoma (PRAME), an immunogenic variant thereof, or an immunogenic fragment of the PRAME or the immunogenic variant thereof.

Abstract: The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of tumor tissues, in particular tumors of the central nervous system (CNS) such as glioma, in particular glioblastoma and which represent targets for therapy or diagnosis of tumor diseases in a subject.

Abstract: The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of tumor tissues, in particular tumors of the central nervous system (CNS) such as glioma, in particular glioblastoma and which represent targets for therapy or diagnosis of tumor diseases in a subject.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training users. The methods, systems, and apparatus include actions of obtaining multiple training modules that each correspond to a different time interval associated with a training program, each training module specifying one or more respective training tasks. Additional actions include identifying a particular training module and providing a notification that the particular training module is available for access. Further actions include receiving a request to access one or more tasks associated with the particular training module and providing one or more particular training tasks. More actions include receiving, at a later time, an indication of completion of the one or more particular training tasks and determining that the corresponding time interval is also associated with the later time. Additional actions include generating a score for the particular training module.