Patents by Inventor Diana E. Ko

Diana E. Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioprosthetic heart valves having adaptive seals to minimize perivalvular leakage
    Patent number: 12089971
    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: September 17, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Qinggang Zeng, Chacphet Limsakoune, Diana E. Ko, Christina M. Aguila
  • BIOPROSTHETIC HEART VALVES HAVING ADAPTIVE SEALS TO MINIMIZE PERIVALVULAR LEAKAGE
    Publication number: 20200352670
    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: Qinggang Zeng, Chacphet Limsakoune, Diana E. Ko, Christina M. Aguila
  • Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage
    Patent number: 10722316
    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: July 28, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Qinggang Zeng, Chacphet Limsakoune, Diana E. Ko, Christina M. Aguila
  • BIOPROSTHETIC HEART VALVES HAVING ADAPTIVE SEALS TO MINIMIZE PARAVALVULAR LEAKAGE
    Publication number: 20180042690
    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.
    Type: Application
    Filed: October 24, 2017
    Publication date: February 15, 2018
    Inventors: Qinggang Zeng, Chacphet Limsakoune, Diana E. Ko, Christina M. Aguila
  • BIOPROSTHETIC HEART VALVES HAVING ADAPTIVE SEALS TO MINIMIZE PARAVALVULAR LEAKAGE
    Publication number: 20150122687
    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Inventors: Qinggang Zeng, Chacphet Limsakoune, Diana E. Ko, Christina M. Aguila