Abstract: The disclosure provides methods for processing nucleic acid populations containing different forms (e.g., RNA and DNA, single-stranded or double-stranded) and/or extents of modification (e.g., cytosine methylation, association with proteins). These methods accommodate multiple forms and/or modifications of nucleic acid in a sample, such that sequence information can be obtained for multiple forms. The methods also preserve the identity of multiple forms or modified states through processing and analysis, such that analysis of sequence can be combined with epigenetic analysis.

Abstract: A bathtub shortener and position stabilizer for maintaining a user in an upright position and inhibiting the motion of sliding out of an upright position while bathing in a bathtub is provided. The bathtub shortener and position stabilizer comprises a main body having at least one side wall, a top wall, and a mounting wall. A combination foot rest and foot pad is securable to one of the side walls of the main body. A securing mechanism secured to the mounting wall of the main body releasably secures the main body to the bathtub in a position contactable by the user wherein the combination foot rest and foot pad are constructed from softer material than the main body and wherein upon releasably securing the main body to the bathtub, the combination foot rest and foot pad face the user allowing the user to contact the combination foot rest and foot pad thereby maintaining the user in an upright position.