Patents by Inventor Diana Nersesian

Diana Nersesian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080234308
    Abstract: The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to ?7 nicotinic acetylcholine receptors also are described.
    Type: Application
    Filed: September 7, 2006
    Publication date: September 25, 2008
    Applicant: Abbott Laboratories
    Inventors: Michael Schrimpf, Kevin Sippy, David Anderson, William Bunnelle, Diana Nersesian
  • Publication number: 20070072892
    Abstract: The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to ?7 nicotinic acetylcholine receptors also are described.
    Type: Application
    Filed: September 7, 2006
    Publication date: March 29, 2007
    Inventors: Michael Schrimpf, Kevin Sippy, David Anderson, William Bunnelle, Diana Nersesian
  • Publication number: 20070060588
    Abstract: Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+—O?; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: June 9, 2006
    Publication date: March 15, 2007
    Inventors: Jianguo Ji, Tao Li, Kathleen Mortell, Michael Schrimpf, Diana Nersesian, Liping Pan, William Bunnelle
  • Publication number: 20060194798
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 5, 2006
    Publication date: August 31, 2006
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Padam Sharma, Youssef Bennani, Michael Curtis
  • Publication number: 20050272728
    Abstract: Compounds of formula (I) wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X?, Y, Y?, Z, Z?, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 6, 2005
    Publication date: December 8, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050272736
    Abstract: Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X?, Y, Y?, Z, and Z? are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 6, 2005
    Publication date: December 8, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050256118
    Abstract: Compounds of formula (I) wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X?, Y, Y?, Z, Z?, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 12, 2004
    Publication date: November 17, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050256309
    Abstract: Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X?, Y, Y?, Z, and Z? are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 12, 2004
    Publication date: November 17, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050245531
    Abstract: Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+—O—; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: June 15, 2005
    Publication date: November 3, 2005
    Inventors: Jianguo Ji, Tao Li, Kathleen Mortell, Michael Schrimpf, Diana Nersesian, Liping Pan, William Bunnelle
  • Publication number: 20050137204
    Abstract: Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+—O?; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 23, 2005
    Inventors: Jianguo Ji, Tao Li, Kathleen Mortell, Michael Schimpf, Diana Nersesian, Liping Pan
  • Publication number: 20050101602
    Abstract: Compounds of formula (I) Z-Ar1—Ar2??(I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: September 16, 2004
    Publication date: May 12, 2005
    Inventors: Anwer Basha, William Bunnelle, Michael Dart, Megan Gallagher, Jianguo Ji, Tao Li, Jennifer Pace, Keith Ryther, Karin Tietje, Kathleen Mortell, Diana Nersesian, Michael Schrimpf